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KRAS is vulnerable to reversible switch-II pocket engagement in cells.
Vasta JD, Peacock DM, Zheng Q, Walker JA, Zhang Z, Zimprich CA, Thomas MR, Beck MT, Binkowski BF, Corona CR, Robers MB, Shokat KM. Vasta JD, et al. Among authors: zheng q. Nat Chem Biol. 2022 Jun;18(6):596-604. doi: 10.1038/s41589-022-00985-w. Epub 2022 Mar 21. Nat Chem Biol. 2022. PMID: 35314814 Free PMC article.
Drugging the Next Undruggable KRAS Allele-Gly12Asp.
Zheng Q, Peacock DM, Shokat KM. Zheng Q, et al. J Med Chem. 2022 Feb 24;65(4):3119-3122. doi: 10.1021/acs.jmedchem.2c00099. Epub 2022 Feb 15. J Med Chem. 2022. PMID: 35167298 Review.
Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes.
Malakoutikhah M, Mahran R, Gooran N, Masoumi A, Lundell K, Liljeblad A, Guiley K, Dai S, Zheng Q, Zhu L, Shokat KM, Kopra K, Härmä H. Malakoutikhah M, et al. Among authors: zheng q. Anal Chem. 2023 Dec 19;95(50):18344-18351. doi: 10.1021/acs.analchem.3c02844. Epub 2023 Dec 7. Anal Chem. 2023. PMID: 38060502 Free PMC article.
7,932 results