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Complexities and paradoxes in understanding the role of dopamine in incentive motivation and instrumental action: Exertion of effort vs. anhedonia.
Salamone JD, Ecevitoglu A, Carratala-Ros C, Presby RE, Edelstein GA, Fleeher R, Rotolo RA, Meka N, Srinath S, Masthay JC, Correa M. Salamone JD, et al. Among authors: edelstein ga. Brain Res Bull. 2022 May;182:57-66. doi: 10.1016/j.brainresbull.2022.01.019. Epub 2022 Feb 10. Brain Res Bull. 2022. PMID: 35151797 Review.
Effects of the atypical antipsychotic and D3/D2 dopamine partial agonist cariprazine on effort-based choice behavior: implications for modeling avolition.
Ecevitoglu A, Edelstein GA, Presby RE, Rotolo RA, Yang JH, Quiles T, Okifo K, Conrad RT, Kovach A, Correa M, Salamone JD. Ecevitoglu A, et al. Among authors: edelstein ga. Psychopharmacology (Berl). 2023 Aug;240(8):1747-1757. doi: 10.1007/s00213-023-06405-8. Epub 2023 Jun 26. Psychopharmacology (Berl). 2023. PMID: 37358806
Effort-related effects of chronic administration of the DA D2 receptor antagonist haloperidol via subcutaneous programmable minipumps: Reversal by co-administration of the adenosine A2A antagonist istradefylline.
Rotolo RA, Ecevitoglu A, Presby RE, Lindgren H, Mombereau C, Nicholas C, Moore A, Edelstein GA, Correa M, Salamone JD. Rotolo RA, et al. Among authors: edelstein ga. Psychopharmacology (Berl). 2023 Oct;240(10):2173-2185. doi: 10.1007/s00213-023-06439-y. Epub 2023 Aug 24. Psychopharmacology (Berl). 2023. PMID: 37615683
Potential therapeutics for effort-related motivational dysfunction: assessing novel atypical dopamine transport inhibitors.
Ecevitoglu A, Meka N, Rotolo RA, Edelstein GA, Srinath S, Beard KR, Carratala-Ros C, Presby RE, Cao J, Okorom A, Newman AH, Correa M, Salamone JD. Ecevitoglu A, et al. Among authors: edelstein ga. Neuropsychopharmacology. 2024 Mar 1. doi: 10.1038/s41386-024-01826-1. Online ahead of print. Neuropsychopharmacology. 2024. PMID: 38429498