Abdelazeem AH - Search Results

1

New 1,2,4-oxadiazole/pyrrolidine hybrids as topoisomerase IV and DNA gyrase inhibitors with promising antibacterial activity.

Frejat FOA, Cao Y, Wang L, Zhai H, Abdelazeem AH, Gomaa HAM, Youssif BGM, Wu C. Frejat FOA, et al. Among authors: abdelazeem ah. Arch Pharm (Weinheim). 2022 Jul;355(7):e2100516. doi: 10.1002/ardp.202100516. Epub 2022 Apr 1. Arch Pharm (Weinheim). 2022. PMID: 35363388

2

Design, synthesis, and anti-inflammatory evaluation of novel diphenylthiazole-thiazolidinone hybrids.

Abdelazeem AH, Salama SA, Maghrabi IA. Abdelazeem AH, et al. Arch Pharm (Weinheim). 2015 Jul;348(7):518-30. doi: 10.1002/ardp.201500104. Epub 2015 May 18. Arch Pharm (Weinheim). 2015. PMID: 25989149

3

Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity.

Abdelrahman MH, Youssif BGM, Abdelgawad MA, Abdelazeem AH, Ibrahim HM, Moustafa AEGA, Treamblu L, Bukhari SNA. Abdelrahman MH, et al. Among authors: abdelazeem ah. Eur J Med Chem. 2017 Feb 15;127:972-985. doi: 10.1016/j.ejmech.2016.11.006. Epub 2016 Nov 5. Eur J Med Chem. 2017. PMID: 27837994

4

Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance.

Zha GF, Qin HL, Youssif BGM, Amjad MW, Raja MAG, Abdelazeem AH, Bukhari SNA. Zha GF, et al. Among authors: abdelazeem ah. Eur J Med Chem. 2017 Jul 28;135:34-48. doi: 10.1016/j.ejmech.2017.04.025. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28431353

5

Novel diphenylthiazole derivatives with multi-target mechanism: Synthesis, docking study, anticancer and anti-inflammatory activities.

Abdelazeem AH, El-Saadi MT, Said EG, Youssif BGM, Omar HA, El-Moghazy SM. Abdelazeem AH, et al. Bioorg Chem. 2017 Dec;75:127-138. doi: 10.1016/j.bioorg.2017.09.009. Epub 2017 Sep 12. Bioorg Chem. 2017. PMID: 28938224

6

Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production.

Youssif BGM, Abdelrahman MH, Abdelazeem AH, Abdelgawad MA, Ibrahim HM, Salem OIA, Mohamed MFA, Treambleau L, Bukhari SNA. Youssif BGM, et al. Among authors: abdelazeem ah. Eur J Med Chem. 2018 Feb 25;146:260-273. doi: 10.1016/j.ejmech.2018.01.042. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407956

7

Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors.

El-Sherief HAM, Youssif BGM, Abbas Bukhari SN, Abdelazeem AH, Abdel-Aziz M, Abdel-Rahman HM. El-Sherief HAM, et al. Among authors: abdelazeem ah. Eur J Med Chem. 2018 Aug 5;156:774-789. doi: 10.1016/j.ejmech.2018.07.024. Epub 2018 Jul 10. Eur J Med Chem. 2018. PMID: 30055463

8

Design, Synthesis and Antiproliferative Evaluation of Novel 1,2,4-Triazole/Schiff Base Hybrids with EGFR and B-RAF Inhibitory Activities.

El-Sherief HAM, Youssif BGM, Abdelazeem AH, Abdel-Aziz M, Abdel-Rahman HM. El-Sherief HAM, et al. Among authors: abdelazeem ah. Anticancer Agents Med Chem. 2019;19(5):697-706. doi: 10.2174/1871520619666181224115346. Anticancer Agents Med Chem. 2019. PMID: 30582484

9

Discovery of novel urea-diarylpyrazole hybrids as dual COX-2/sEH inhibitors with improved anti-inflammatory activity and highly reduced cardiovascular risks.

Abdelazeem AH, Safi El-Din AG, Abdel-Fattah MM, Amin NH, El-Moghazy SM, El-Saadi MT. Abdelazeem AH, et al. Eur J Med Chem. 2020 Nov 1;205:112662. doi: 10.1016/j.ejmech.2020.112662. Epub 2020 Jul 24. Eur J Med Chem. 2020. PMID: 32763463

10

Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity.

Mohamed FAM, Gomaa HAM, Hendawy OM, Ali AT, Farghaly HS, Gouda AM, Abdelazeem AH, Abdelrahman MH, Trembleau L, Youssif BGM. Mohamed FAM, et al. Among authors: abdelazeem ah. Bioorg Chem. 2021 Jul;112:104960. doi: 10.1016/j.bioorg.2021.104960. Epub 2021 May 1. Bioorg Chem. 2021. PMID: 34020242

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