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Lyophilized Filovirus Glycoprotein Vaccines: Peroxides in a Vaccine Formulation with Polysorbate 80-Containing Adjuvant are Associated with Reduced Neutralizing Antibody Titers in Both Mice and Non-Human Primates.
Preston KB, Wong TAS, Lieberman MM, To A, Lai CY, Granados A, Thomasson H, Misamore J, Yalley-Ogunro J, Cabus M, Andersen H, Donini O, Lehrer AT, Randolph TW. Preston KB, et al. J Pharm Sci. 2022 Dec;111(12):3424-3434. doi: 10.1016/j.xphs.2022.05.017. Epub 2022 May 21. J Pharm Sci. 2022. PMID: 35609629