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NuRD complex recruitment to Thpok mediates CD4+ T cell lineage differentiation.
Gao Y, Zamisch M, Vacchio M, Chopp L, Ciucci T, Paine EL, Lyons GC, Nie J, Xiao Q, Zvezdova E, Love PE, Vinson CR, Jenkins LM, Bosselut R. Gao Y, et al. Sci Immunol. 2022 Jun 10;7(72):eabn5917. doi: 10.1126/sciimmunol.abn5917. Epub 2022 Jun 10. Sci Immunol. 2022. PMID: 35687698 Free PMC article.
A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation.
Vacchio MS, Ciucci T, Gao Y, Watanabe M, Balmaceno-Criss M, McGinty MT, Huang A, Xiao Q, McConkey C, Zhao Y, Shetty J, Tran B, Pepper M, Vahedi G, Jenkins MK, McGavern DB, Bosselut R. Vacchio MS, et al. Among authors: gao y. Immunity. 2019 Sep 17;51(3):465-478.e6. doi: 10.1016/j.immuni.2019.06.023. Epub 2019 Aug 15. Immunity. 2019. PMID: 31422869 Free PMC article.
Zfp281 and Zfp148 control CD4+ T cell thymic development and TH2 functions.
Chopp LB, Zhu X, Gao Y, Nie J, Singh J, Kumar P, Young KZ, Patel S, Li C, Balmaceno-Criss M, Vacchio MS, Wang MM, Livak F, Merchant JL, Wang L, Kelly MC, Zhu J, Bosselut R. Chopp LB, et al. Among authors: gao y. Sci Immunol. 2023 Nov 10;8(89):eadi9066. doi: 10.1126/sciimmunol.adi9066. Epub 2023 Nov 10. Sci Immunol. 2023. PMID: 37948511
USP22 is a positive regulator of NFATc2 on promoting IL2 expression.
Gao Y, Lin F, Xu P, Nie J, Chen Z, Su J, Tang J, Wu Q, Li Y, Guo Z, Gao Z, Li D, Shen J, Ge S, Tsun A, Li B. Gao Y, et al. Among authors: gao z. FEBS Lett. 2014 Mar 18;588(6):878-83. doi: 10.1016/j.febslet.2014.02.016. Epub 2014 Feb 20. FEBS Lett. 2014. PMID: 24561192 Free article.
The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation.
Yang J, Wei P, Barbi J, Huang Q, Yang E, Bai Y, Nie J, Gao Y, Tao J, Lu Y, Xie C, Hou X, Ren J, Wu X, Meng J, Zhang Y, Fu J, Kou W, Gao Y, Chen Z, Liang R, Tsun A, Li D, Guo W, Zhang S, Zheng SG, Niu J, Galardy P, Tong X, Shi G, Li H, Pan F, Li B. Yang J, et al. Among authors: gao y. EMBO Rep. 2020 Sep 3;21(9):e50308. doi: 10.15252/embr.202050308. Epub 2020 Jul 9. EMBO Rep. 2020. PMID: 32644293 Free PMC article.
The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.
Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B. Chen Z, et al. Among authors: gao z, gao y. Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006. Immunity. 2013. PMID: 23973223 Free PMC article.
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