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Engineered U1 snRNAs to modulate alternatively spliced exons.
Methods. 2022 Sep;205:140-148. doi: 10.1016/j.ymeth.2022.06.008. Epub 2022 Jun 25.
Methods. 2022.
PMID: 35764245
Free article.
RNA-targeting CRISPR systems from metagenomic discovery to transcriptomic engineering.
Smargon AA, Shi YJ, Yeo GW.
Smargon AA, et al.
Nat Cell Biol. 2020 Feb;22(2):143-150. doi: 10.1038/s41556-019-0454-7. Epub 2020 Feb 3.
Nat Cell Biol. 2020.
PMID: 32015437
Free PMC article.
Review.
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Crosstalk between CRISPR-Cas9 and the human transcriptome.
Smargon AA, Madrigal AA, Yee BA, Dong KD, Mueller JR, Yeo GW.
Smargon AA, et al.
Nat Commun. 2022 Mar 2;13(1):1125. doi: 10.1038/s41467-022-28719-5.
Nat Commun. 2022.
PMID: 35236841
Free PMC article.
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Diversity and evolution of class 2 CRISPR-Cas systems.
Shmakov S, Smargon A, Scott D, Cox D, Pyzocha N, Yan W, Abudayyeh OO, Gootenberg JS, Makarova KS, Wolf YI, Severinov K, Zhang F, Koonin EV.
Shmakov S, et al.
Nat Rev Microbiol. 2017 Mar;15(3):169-182. doi: 10.1038/nrmicro.2016.184. Epub 2017 Jan 23.
Nat Rev Microbiol. 2017.
PMID: 28111461
Free PMC article.
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Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28.
Smargon AA, Cox DBT, Pyzocha NK, Zheng K, Slaymaker IM, Gootenberg JS, Abudayyeh OA, Essletzbichler P, Shmakov S, Makarova KS, Koonin EV, Zhang F.
Smargon AA, et al.
Mol Cell. 2017 Feb 16;65(4):618-630.e7. doi: 10.1016/j.molcel.2016.12.023. Epub 2017 Jan 5.
Mol Cell. 2017.
PMID: 28065598
Free PMC article.
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Human chitotriosidase polymorphisms G354R and A442V associated with reduced enzyme activity.
Lee P, Waalen J, Crain K, Smargon A, Beutler E.
Lee P, et al.
Blood Cells Mol Dis. 2007 Nov-Dec;39(3):353-60. doi: 10.1016/j.bcmd.2007.06.013. Epub 2007 Aug 10.
Blood Cells Mol Dis. 2007.
PMID: 17693102
Free PMC article.
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Programmable macromolecule-based RNA-targeting therapies to treat human neurological disorders.
Morelli KH, Smargon AA, Yeo GW.
Morelli KH, et al. Among authors: smargon aa.
RNA. 2023 Apr;29(4):489-497. doi: 10.1261/rna.079519.122. Epub 2023 Jan 24.
RNA. 2023.
PMID: 36693761
Free PMC article.
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