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Modulation of the Itaconate Pathway Attenuates Murine Lupus.
Blanco LP, Patino-Martinez E, Nakabo S, Zhang M, Pedersen HL, Wang X, Carmona-Rivera C, Claybaugh D, Yu ZX, Desta E, Kaplan MJ. Blanco LP, et al. Among authors: yu zx. Arthritis Rheumatol. 2022 Dec;74(12):1971-1983. doi: 10.1002/art.42284. Epub 2022 Nov 6. Arthritis Rheumatol. 2022. PMID: 35791960
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.
Goel RR, Wang X, O'Neil LJ, Nakabo S, Hasneen K, Gupta S, Wigerblad G, Blanco LP, Kopp JB, Morasso MI, Kotenko SV, Yu ZX, Carmona-Rivera C, Kaplan MJ. Goel RR, et al. Among authors: yu zx. Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5409-5419. doi: 10.1073/pnas.1916897117. Epub 2020 Feb 24. Proc Natl Acad Sci U S A. 2020. PMID: 32094169 Free PMC article.
The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses.
Fredriksson K, Mishra A, Lam JK, Mushaben EM, Cuento RA, Meyer KS, Yao X, Keeran KJ, Nugent GZ, Qu X, Yu ZX, Yang Y, Raghavachari N, Dagur PK, McCoy JP, Levine SJ. Fredriksson K, et al. Among authors: yu zx. J Immunol. 2014 May 15;192(10):4497-509. doi: 10.4049/jimmunol.1301234. Epub 2014 Apr 14. J Immunol. 2014. PMID: 24733846 Free PMC article. Clinical Trial.
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.
Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C. Arbore G, et al. Among authors: yu zx. Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210. Science. 2016. PMID: 27313051 Free PMC article.
Low-density lipoprotein receptor-related protein 1 attenuates house dust mite-induced eosinophilic airway inflammation by suppressing dendritic cell-mediated adaptive immune responses.
Mishra A, Yao X, Saxena A, Gordon EM, Kaler M, Cuento RA, Barochia AV, Dagur PK, McCoy JP, Keeran KJ, Jeffries KR, Qu X, Yu ZX, Levine SJ. Mishra A, et al. Among authors: yu zx. J Allergy Clin Immunol. 2018 Oct;142(4):1066-1079.e6. doi: 10.1016/j.jaci.2017.10.044. Epub 2017 Dec 21. J Allergy Clin Immunol. 2018. PMID: 29274414 Free PMC article.
514 results