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TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination.
Cantelli G, Orgaz JL, Rodriguez-Hernandez I, Karagiannis P, Maiques O, Matias-Guiu X, Nestle FO, Marti RM, Karagiannis SN, Sanz-Moreno V. Cantelli G, et al. Among authors: maiques o. Curr Biol. 2015 Nov 16;25(22):2899-914. doi: 10.1016/j.cub.2015.09.054. Epub 2015 Oct 29. Curr Biol. 2015. PMID: 26526369 Free PMC article.
T-type calcium channels drive migration/invasion in BRAFV600E melanoma cells through Snail1.
Maiques O, Barceló C, Panosa A, Pijuan J, Orgaz JL, Rodriguez-Hernandez I, Matas-Nadal C, Tell G, Vilella R, Fabra A, Puig S, Sanz-Moreno V, Matias-Guiu X, Canti C, Herreros J, Marti RM, Macià A. Maiques O, et al. Pigment Cell Melanoma Res. 2018 Jul;31(4):484-495. doi: 10.1111/pcmr.12690. Epub 2018 Feb 18. Pigment Cell Melanoma Res. 2018. PMID: 29385656 Free article.
Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment.
Georgouli M, Herraiz C, Crosas-Molist E, Fanshawe B, Maiques O, Perdrix A, Pandya P, Rodriguez-Hernandez I, Ilieva KM, Cantelli G, Karagiannis P, Mele S, Lam H, Josephs DH, Matias-Guiu X, Marti RM, Nestle FO, Orgaz JL, Malanchi I, Fruhwirth GO, Karagiannis SN, Sanz-Moreno V. Georgouli M, et al. Among authors: maiques o. Cell. 2019 Feb 7;176(4):757-774.e23. doi: 10.1016/j.cell.2018.12.038. Epub 2019 Jan 31. Cell. 2019. PMID: 30712866 Free PMC article.
Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease.
Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J, Bedi KC Jr, Margulies KB, Sanz-Moreno V, Hobbs A, Hodivala-Dilke K. Dukinfield M, et al. Among authors: maiques o. J Pathol. 2019 Dec;249(4):523-535. doi: 10.1002/path.5340. Epub 2019 Oct 30. J Pathol. 2019. PMID: 31424556 Free PMC article.
Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition.
López-Luque J, Bertran E, Crosas-Molist E, Maiques O, Malfettone A, Caja L, Serrano T, Ramos E, Sanz-Moreno V, Fabregat I. López-Luque J, et al. Among authors: maiques o. Cancer Lett. 2019 Nov 1;464:15-24. doi: 10.1016/j.canlet.2019.08.011. Epub 2019 Aug 26. Cancer Lett. 2019. PMID: 31465839 Free PMC article.
Recent advances in tissue imaging for cancer research.
Maiques O, Georgouli M, Sanz-Moreno V. Maiques O, et al. F1000Res. 2019 Nov 25;8:F1000 Faculty Rev-1980. doi: 10.12688/f1000research.19037.1. eCollection 2019. F1000Res. 2019. PMID: 31824652 Free PMC article. Review.
Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance.
Orgaz JL, Crosas-Molist E, Sadok A, Perdrix-Rosell A, Maiques O, Rodriguez-Hernandez I, Monger J, Mele S, Georgouli M, Bridgeman V, Karagiannis P, Lee R, Pandya P, Boehme L, Wallberg F, Tape C, Karagiannis SN, Malanchi I, Sanz-Moreno V. Orgaz JL, et al. Among authors: maiques o. Cancer Cell. 2020 Jan 13;37(1):85-103.e9. doi: 10.1016/j.ccell.2019.12.003. Cancer Cell. 2020. PMID: 31935375 Free PMC article.
Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells.
Wong PP, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O, Meng YM, Meng Q, Bodrug N, Dukinfield MS, Reynolds LE, Elia G, Clear A, Harwood C, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Matchett KP, Henderson NC, Szlosarek PW, Dreger SA, Smith S, Jones JL, Gribben JG, Cutillas PR, Meier P, Sanz-Moreno V, Hodivala-Dilke KM. Wong PP, et al. Among authors: maiques o. Cell. 2020 Jun 11;181(6):1346-1363.e21. doi: 10.1016/j.cell.2020.02.003. Epub 2020 May 29. Cell. 2020. PMID: 32473126 Free article.
First-in-Human Study of AT13148, a Dual ROCK-AKT Inhibitor in Patients with Solid Tumors.
McLeod R, Kumar R, Papadatos-Pastos D, Mateo J, Brown JS, Garces AHI, Ruddle R, Decordova S, Jueliger S, Ferraldeschi R, Maiques O, Sanz-Moreno V, Jones P, Traub S, Halbert G, Mellor S, Swales KE, Raynaud FI, Garrett MD, Banerji U. McLeod R, et al. Among authors: maiques o. Clin Cancer Res. 2020 Sep 15;26(18):4777-4784. doi: 10.1158/1078-0432.CCR-20-0700. Epub 2020 Jul 2. Clin Cancer Res. 2020. PMID: 32616501 Free PMC article. Clinical Trial.
39 results