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The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis.
De Marco Zompit M, Esteban MT, Mooser C, Adam S, Rossi SE, Jeanrenaud A, Leimbacher PA, Fink D, Shorrocks AK, Blackford AN, Durocher D, Stucki M. De Marco Zompit M, et al. Among authors: shorrocks ak. Nat Commun. 2022 Jul 16;13(1):4143. doi: 10.1038/s41467-022-31865-5. Nat Commun. 2022. PMID: 35842428 Free PMC article.
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M. Leimbacher PA, et al. Among authors: shorrocks ak. Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18. Mol Cell. 2019. PMID: 30898438 Free PMC article.
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation.
Mooser C, Symeonidou IE, Leimbacher PA, Ribeiro A, Shorrocks AK, Jungmichel S, Larsen SC, Knechtle K, Jasrotia A, Zurbriggen D, Jeanrenaud A, Leikauf C, Fink D, Nielsen ML, Blackford AN, Stucki M. Mooser C, et al. Among authors: shorrocks ak. Nat Commun. 2020 Jan 8;11(1):123. doi: 10.1038/s41467-019-13981-x. Nat Commun. 2020. PMID: 31913317 Free PMC article.