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Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression.
Grima-Reyes M, Vandenberghe A, Nemazanyy I, Meola P, Paul R, Reverso-Meinietti J, Martinez-Turtos A, Nottet N, Chan WK, Lorenzi PL, Marchetti S, Ricci JE, Chiche J. Grima-Reyes M, et al. Among authors: nemazanyy i. Sci Adv. 2022 Jul 8;8(27):eabn6491. doi: 10.1126/sciadv.abn6491. Epub 2022 Jul 6. Sci Adv. 2022. PMID: 35857457 Free PMC article.
mTOR inhibition suppresses salinomycin-induced ferroptosis in breast cancer stem cells by ironing out mitochondrial dysfunctions.
Cosialls E, Pacreau E, Duruel C, Ceccacci S, Elhage R, Desterke C, Roger K, Guerrera C, Ducloux R, Souquere S, Pierron G, Nemazanyy I, Kelly M, Dalmas E, Chang Y, Goffin V, Mehrpour M, Hamaï A. Cosialls E, et al. Among authors: nemazanyy i. Cell Death Dis. 2023 Nov 15;14(11):744. doi: 10.1038/s41419-023-06262-5. Cell Death Dis. 2023. PMID: 37968262 Free PMC article.
PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption.
Ladraa S, Zerbib L, Bayard C, Fraissenon A, Venot Q, Morin G, Garneau AP, Isnard P, Chapelle C, Hoguin C, Fraitag S, Duong JP, Guibaud L, Besançon A, Kaltenbach S, Villarese P, Asnafi V, Broissand C, Goudin N, Dussiot M, Nemazanyy I, Viel T, Autret G, Cruciani-Guglielmacci C, Denom J, Bruneau J, Tavitian B, Legendre C, Dairou J, Lacorte JM, Levy P, Pende M, Polak M, Canaud G. Ladraa S, et al. Among authors: nemazanyy i. Sci Adv. 2022 Dec 9;8(49):eade7823. doi: 10.1126/sciadv.ade7823. Epub 2022 Dec 9. Sci Adv. 2022. PMID: 36490341 Free PMC article.
Cell stress response impairs de novo NAD+ biosynthesis in the kidney.
Bignon Y, Rinaldi A, Nadour Z, Poindessous V, Nemazanyy I, Lenoir O, Fohlen B, Weill-Raynal P, Hertig A, Karras A, Galichon P, Naesens M, Anglicheau D, Cippà PE, Pallet N. Bignon Y, et al. Among authors: nemazanyy i. JCI Insight. 2022 Jan 11;7(1):e153019. doi: 10.1172/jci.insight.153019. JCI Insight. 2022. PMID: 34793337 Free PMC article.
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD.
Donne R, Saroul-Ainama M, Cordier P, Hammoutene A, Kabore C, Stadler M, Nemazanyy I, Galy-Fauroux I, Herrag M, Riedl T, Chansel-Da Cruz M, Caruso S, Bonnafous S, Öllinger R, Rad R, Unger K, Tran A, Couty JP, Gual P, Paradis V, Celton-Morizur S, Heikenwalder M, Revy P, Desdouets C. Donne R, et al. Among authors: nemazanyy i. Dev Cell. 2022 Jul 25;57(14):1728-1741.e6. doi: 10.1016/j.devcel.2022.06.003. Epub 2022 Jun 28. Dev Cell. 2022. PMID: 35768000 Free article.
Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction.
Lamarthée B, Marchal A, Charbonnier S, Blein T, Leon J, Martin E, Rabaux L, Vogt K, Titeux M, Delville M, Vinçon H, Six E, Pallet N, Michonneau D, Anglicheau D, Legendre C, Taupin JL, Nemazanyy I, Sawitzki B, Latour S, Cavazzana M, André I, Zuber J. Lamarthée B, et al. Among authors: nemazanyy i. Nat Commun. 2021 Nov 8;12(1):6446. doi: 10.1038/s41467-021-26844-1. Nat Commun. 2021. PMID: 34750385 Free PMC article.
71 results