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Possible mechanism for improving the endogenous immune system through the blockade of peripheral μ-opioid receptors by treatment with naldemedine.
Gondoh E, Hamada Y, Mori T, Iwazawa Y, Shinohara A, Narita M, Sato D, Tezuka H, Yamauchi T, Tsujimura M, Yoshida S, Tanaka K, Yamashita K, Akatori H, Higashiyama K, Arakawa K, Suda Y, Miyano K, Iseki M, Inada E, Kuzumaki N, Narita M. Gondoh E, et al. Among authors: suda y. Br J Cancer. 2022 Nov;127(8):1565-1574. doi: 10.1038/s41416-022-01928-x. Epub 2022 Aug 9. Br J Cancer. 2022. PMID: 35945243 Free PMC article.
Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c.
Narita M, Shimura E, Nagasawa A, Aiuchi T, Suda Y, Hamada Y, Ikegami D, Iwasawa C, Arakawa K, Igarashi K, Kuzumaki N, Yoshioka Y, Ochiya T, Takeshima H, Ushijima T, Narita M. Narita M, et al. Among authors: suda y. PLoS One. 2017 Feb 22;12(2):e0172115. doi: 10.1371/journal.pone.0172115. eCollection 2017. PLoS One. 2017. PMID: 28225782 Free PMC article.
Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease.
Kuzumaki N, Suda Y, Iwasawa C, Narita M, Sone T, Watanabe M, Maekawa A, Matsumoto T, Akamatsu W, Igarashi K, Tamura H, Takeshima H, Tawfik VL, Ushijima T, Hattori N, Okano H, Narita M. Kuzumaki N, et al. Among authors: suda y. Brain. 2019 Jun 1;142(6):1675-1689. doi: 10.1093/brain/awz084. Brain. 2019. PMID: 31135049
Further investigation of the rapid-onset and short-duration action of the G protein-biased μ-ligand oliceridine.
Mori T, Takemura Y, Arima T, Iwase Y, Narita M, Miyano K, Hamada Y, Suda Y, Matsuzawa A, Sugita K, Matsumura S, Sasaki S, Yamauchi T, Higashiyama K, Uezono Y, Yamazaki M, Kuzumaki N, Narita M. Mori T, et al. Among authors: suda y. Biochem Biophys Res Commun. 2021 Jan 1;534:988-994. doi: 10.1016/j.bbrc.2020.10.053. Epub 2020 Nov 1. Biochem Biophys Res Commun. 2021. PMID: 33139013
Direct evidence that the brain reward system is involved in the control of scratching behaviors induced by acute and chronic itch.
Setsu T, Hamada Y, Oikawa D, Mori T, Ishiuji Y, Sato D, Narita M, Miyazaki S, Furuta E, Suda Y, Sakai H, Ochiya T, Tezuka H, Iseki M, Inada E, Yamanaka A, Kuzumaki N, Narita M. Setsu T, et al. Among authors: suda y. Biochem Biophys Res Commun. 2021 Jan 1;534:624-631. doi: 10.1016/j.bbrc.2020.11.030. Epub 2020 Nov 19. Biochem Biophys Res Commun. 2021. PMID: 33220930
673 results