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Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice.
Strong R, Miller RA, Cheng CJ, Nelson JF, Gelfond J, Allani SK, Diaz V, Dorigatti AO, Dorigatti J, Fernandez E, Galecki A, Ginsburg B, Hamilton KL, Javors MA, Kornfeld K, Kaeberlein M, Kumar S, Lombard DB, Lopez-Cruzan M, Miller BF, Rabinovitch P, Reifsnyder P, Rosenthal NA, Bogue MA, Salmon AB, Suh Y, Verdin E, Weissbach H, Newman J, Maccchiarini F, Harrison DE. Strong R, et al. Among authors: kaeberlein m. Aging Cell. 2022 Dec;21(12):e13724. doi: 10.1111/acel.13724. Epub 2022 Sep 30. Aging Cell. 2022. PMID: 36179270 Free PMC article.
Medicine: grapes versus gluttony.
Kaeberlein M, Rabinovitch PS. Kaeberlein M, et al. Nature. 2006 Nov 16;444(7117):280-1. doi: 10.1038/nature05308. Nature. 2006. PMID: 17086197 No abstract available.
Trinations aging symposium.
Kaeberlein M, Kennedy BK, Liu X, Suh Y, Zhou Z. Kaeberlein M, et al. Mech Ageing Dev. 2011 Jun-Jul;132(6-7):348-52. doi: 10.1016/j.mad.2011.07.001. Epub 2011 Jul 13. Mech Ageing Dev. 2011. PMID: 21771608 Review.
Sir2 deletion prevents lifespan extension in 32 long-lived mutants.
Delaney JR, Sutphin GL, Dulken B, Sim S, Kim JR, Robison B, Schleit J, Murakami CJ, Carr D, An EH, Choi E, Chou A, Fletcher M, Jelic M, Liu B, Lockshon D, Moller RM, Pak DN, Peng Q, Peng ZJ, Pham KM, Sage M, Solanky A, Steffen KK, Tsuchiya M, Tsuchiyama S, Johnson S, Raabe C, Suh Y, Zhou Z, Liu X, Kennedy BK, Kaeberlein M. Delaney JR, et al. Among authors: kaeberlein m. Aging Cell. 2011 Dec;10(6):1089-91. doi: 10.1111/j.1474-9726.2011.00742.x. Epub 2011 Oct 3. Aging Cell. 2011. PMID: 21902802 Free PMC article.
Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.
Ramos FJ, Chen SC, Garelick MG, Dai DF, Liao CY, Schreiber KH, MacKay VL, An EH, Strong R, Ladiges WC, Rabinovitch PS, Kaeberlein M, Kennedy BK. Ramos FJ, et al. Among authors: kaeberlein m. Sci Transl Med. 2012 Jul 25;4(144):144ra103. doi: 10.1126/scitranslmed.3003802. Sci Transl Med. 2012. PMID: 22837538 Free PMC article.
mTOR is a key modulator of ageing and age-related disease.
Johnson SC, Rabinovitch PS, Kaeberlein M. Johnson SC, et al. Among authors: kaeberlein m. Nature. 2013 Jan 17;493(7432):338-45. doi: 10.1038/nature11861. Nature. 2013. PMID: 23325216 Free PMC article. Review.
Molecular mechanisms underlying genotype-dependent responses to dietary restriction.
Schleit J, Johnson SC, Bennett CF, Simko M, Trongtham N, Castanza A, Hsieh EJ, Moller RM, Wasko BM, Delaney JR, Sutphin GL, Carr D, Murakami CJ, Tocchi A, Xian B, Chen W, Yu T, Goswami S, Higgins S, Holmberg M, Jeong KS, Kim JR, Klum S, Liao E, Lin MS, Lo W, Miller H, Olsen B, Peng ZJ, Pollard T, Pradeep P, Pruett D, Rai D, Ros V, Singh M, Spector BL, Vander Wende H, An EH, Fletcher M, Jelic M, Rabinovitch PS, MacCoss MJ, Han JD, Kennedy BK, Kaeberlein M. Schleit J, et al. Among authors: kaeberlein m. Aging Cell. 2013 Dec;12(6):1050-61. doi: 10.1111/acel.12130. Epub 2013 Aug 11. Aging Cell. 2013. PMID: 23837470 Free PMC article.
Preserving youth: does rapamycin deliver?
Johnson SC, Martin GM, Rabinovitch PS, Kaeberlein M. Johnson SC, et al. Among authors: kaeberlein m. Sci Transl Med. 2013 Nov 13;5(211):211fs40. doi: 10.1126/scitranslmed.3007316. Sci Transl Med. 2013. PMID: 24225941 Free PMC article.
Modulating mTOR in aging and health.
Johnson SC, Sangesland M, Kaeberlein M, Rabinovitch PS. Johnson SC, et al. Among authors: kaeberlein m. Interdiscip Top Gerontol. 2015;40:107-27. doi: 10.1159/000364974. Epub 2014 Oct 13. Interdiscip Top Gerontol. 2015. PMID: 25341517 Free article. Review.
263 results