Shahin MI - Search Results

1

Novel sulfonamide-indolinone hybrids targeting mitochondrial respiration of breast cancer cells.

Helmy SWA, Abdel-Aziz AK, Dokla EME, Ahmed TE, Hatem Y, Abdel Rahman EA, Sharaky M, Shahin MI, Elrazaz EZ, Serya RAT, Henary M, Ali SS, Abou El Ella DA. Helmy SWA, et al. Among authors: shahin mi. Eur J Med Chem. 2024 Mar 15;268:116255. doi: 10.1016/j.ejmech.2024.116255. Epub 2024 Feb 17. Eur J Med Chem. 2024. PMID: 38401190

2

1,2,4-Triazole-Tethered Indolinones as New Cancer-Fighting Small Molecules Targeting VEGFR-2: Synthesis, Biological Evaluations and Molecular Docking.

Elsawi AE, Shahin MI, Elbendary HA, Al-Warhi T, Hassan FE, Eldehna WM. Elsawi AE, et al. Among authors: shahin mi. Pharmaceuticals (Basel). 2024 Jan 8;17(1):81. doi: 10.3390/ph17010081. Pharmaceuticals (Basel). 2024. PMID: 38256914 Free PMC article.

3

Targeting apoptosis; design, synthesis and biological evaluation of new benzoxazole and thiazole based derivatives.

Helmy SW, Shahin MI, Samir N, Lasheen DS, Ella DAAE. Helmy SW, et al. Among authors: shahin mi. BMC Chem. 2024 Jan 3;18(1):1. doi: 10.1186/s13065-023-01101-2. BMC Chem. 2024. PMID: 38173026 Free PMC article.

4

Novel indolinone-tethered benzothiophenes as anti-tubercular agents against MDR/XDR M. tuberculosis: Design, synthesis, biological evaluation and in vivo pharmacokinetic study.

Eldehna WM, Mahmoud ST, Elshnawey ER, Elsayed ZM, Majrashi TA, El-Ashrey MK, Rashed M, Hemeda LR, Shoun AA, Elkaeed EB, El Hassab MA, Abdel-Aziz MM, Shahin MI. Eldehna WM, et al. Among authors: shahin mi. Bioorg Chem. 2024 Feb;143:107009. doi: 10.1016/j.bioorg.2023.107009. Epub 2023 Nov 29. Bioorg Chem. 2024. PMID: 38070474

5

Design and synthesis of benzo[b]thiophene-based hybrids as novel antitubercular agents against MDR/XDR Mycobacterium tuberculosis.

Al-Warhi T, Rashad NM, Almahli H, Abdel-Aziz MM, Elsayed ZM, Shahin MI, Eldehna WM. Al-Warhi T, et al. Among authors: shahin mi. Arch Pharm (Weinheim). 2024 Feb;357(2):e2300529. doi: 10.1002/ardp.202300529. Epub 2023 Nov 9. Arch Pharm (Weinheim). 2024. PMID: 37946574

6

Narrative review on century of respiratory pandemics from Spanish flu to COVID-19 and impact of nanotechnology on COVID-19 diagnosis and immune system boosting.

Elkhatib WF, Abdelkareem SS, Khalaf WS, Shahin MI, Elfadil D, Alhazmi A, El-Batal AI, El-Sayyad GS. Elkhatib WF, et al. Among authors: shahin mi. Virol J. 2022 Oct 24;19(1):167. doi: 10.1186/s12985-022-01902-2. Virol J. 2022. PMID: 36280866 Free PMC article. Review.

7

Novel 1,3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and anticancer agents through selectively targeting COX-2.

Shaker AMM, Shahin MI, AboulMagd AM, Abdel Aleem SA, Abdel-Rahman HM, Abou El Ella DA. Shaker AMM, et al. Among authors: shahin mi. Bioorg Chem. 2022 Dec;129:106143. doi: 10.1016/j.bioorg.2022.106143. Epub 2022 Sep 11. Bioorg Chem. 2022. PMID: 36191430

8

Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinoma.

Shahin MI, Roy J, Hanafi M, Wang D, Luesakul U, Chai Y, Muangsin N, Lasheen DS, Abou El Ella DA, Abouzid KA, Neamati N. Shahin MI, et al. Eur J Med Chem. 2018 Jul 15;155:516-530. doi: 10.1016/j.ejmech.2018.05.042. Epub 2018 May 29. Eur J Med Chem. 2018. PMID: 29908444

9

Design, synthesis and biological evaluation of type-II VEGFR-2 inhibitors based on quinoxaline scaffold.

Shahin MI, Abou El Ella DA, Ismail NS, Abouzid KA. Shahin MI, et al. Bioorg Chem. 2014 Oct;56:16-26. doi: 10.1016/j.bioorg.2014.05.010. Epub 2014 May 28. Bioorg Chem. 2014. PMID: 24922538

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