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Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3.
Shvartsbart A, Roach JJ, Witten MR, Koblish H, Harris JJ, Covington M, Hess R, Lin L, Frascella M, Truong L, Leffet L, Conlen P, Beshad E, Klabe R, Katiyar K, Kaldon L, Young-Sciame R, He X, Petusky S, Chen KJ, Horsey A, Lei HT, Epling LB, Deller MC, Vechorkin O, Yao W. Shvartsbart A, et al. Among authors: petusky s. J Med Chem. 2022 Nov 24;65(22):15433-15442. doi: 10.1021/acs.jmedchem.2c01366. Epub 2022 Nov 10. J Med Chem. 2022. PMID: 36356320
The Effect of Renal Impairment on the Pharmacokinetics and Safety of Itacitinib.
Srinivas N, Barbour AM, Epstein N, Zhou G, Petusky S, Xun Z, Yuska B, Marbury T, Chen X, Yeleswaram S, Punwani N. Srinivas N, et al. Among authors: petusky s. J Clin Pharmacol. 2020 Aug;60(8):1022-1029. doi: 10.1002/jcph.1601. Epub 2020 Mar 9. J Clin Pharmacol. 2020. PMID: 32149388 Free PMC article.
Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment.
Miller LM, Mayer SC, Berger DM, Boschelli DH, Boschelli F, Di L, Du X, Dutia M, Floyd MB, Johnson M, Kenny CH, Krishnamurthy G, Moy F, Petusky S, Tkach D, Torres N, Wu B, Xu W. Miller LM, et al. Among authors: petusky s. Bioorg Med Chem Lett. 2009 Jan 1;19(1):62-6. doi: 10.1016/j.bmcl.2008.11.037. Epub 2008 Nov 17. Bioorg Med Chem Lett. 2009. PMID: 19041240
Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment.
Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W. Mayer SC, et al. Among authors: petusky s. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. doi: 10.1016/j.bmcl.2008.04.044. Epub 2008 Apr 25. Bioorg Med Chem Lett. 2008. PMID: 18501599
Integrity profiling of high throughput screening hits using LC-MS and related techniques.
Kerns EH, Di L, Bourassa J, Gross J, Huang N, Liu H, Kleintop T, Nogle L, Mallis L, Petucci C, Petusky S, Tischler M, Sabus C, Sarkahian A, Young M, Zhang MY, Huryn D, McConnell O, Carter G. Kerns EH, et al. Among authors: petusky s. Comb Chem High Throughput Screen. 2005 Sep;8(6):459-66. doi: 10.2174/1386207054867283. Comb Chem High Throughput Screen. 2005. PMID: 16178805 Review.
Synthesis, characterization and evaluation of pro-drugs of VLA-4 antagonists.
Huryn DM, Ashwell S, Baudy R, Dressen DB, Gallaway W, Grant FS, Konradi A, Ley RW, Petusky S, Pleiss MA, Sarantakis D, Semko CM, Sherman MM, Tio C, Zhang L. Huryn DM, et al. Among authors: petusky s. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1651-4. doi: 10.1016/j.bmcl.2004.01.062. Bioorg Med Chem Lett. 2004. PMID: 15026043
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