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Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models.
Staderini M, Vanni S, Baldeschi AC, Giachin G, Zattoni M, Celauro L, Ferracin C, Bistaffa E, Moda F, Pérez DI, Martínez A, Martín MA, Martín-Cámara O, Cores Á, Bianchini G, Kammerer R, Menéndez JC, Legname G, Bolognesi ML. Staderini M, et al. Among authors: giachin g. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114923. doi: 10.1016/j.ejmech.2022.114923. Epub 2022 Nov 15. Eur J Med Chem. 2023. PMID: 36423450 Free article.
Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance.
Colini Baldeschi A, Zattoni M, Vanni S, Nikolic L, Ferracin C, La Sala G, Summa M, Bertorelli R, Bertozzi SM, Giachin G, Carloni P, Bolognesi ML, De Vivo M, Legname G. Colini Baldeschi A, et al. Among authors: giachin g. J Med Chem. 2022 Jul 14;65(13):8998-9010. doi: 10.1021/acs.jmedchem.2c00205. Epub 2022 Jun 30. J Med Chem. 2022. PMID: 35771181 Free PMC article.
Synthetic prions and other human neurodegenerative proteinopathies.
Le NT, Narkiewicz J, Aulić S, Salzano G, Tran HT, Scaini D, Moda F, Giachin G, Legname G. Le NT, et al. Among authors: giachin g. Virus Res. 2015 Sep 2;207:25-37. doi: 10.1016/j.virusres.2014.10.020. Epub 2014 Oct 31. Virus Res. 2015. PMID: 25449570 Review.
Structural and dynamical determinants of a β-sheet-enriched intermediate involved in amyloid fibrillar assembly of human prion protein.
Russo L, Salzano G, Corvino A, Bistaffa E, Moda F, Celauro L, D'Abrosca G, Isernia C, Milardi D, Giachin G, Malgieri G, Legname G, Fattorusso R. Russo L, et al. Among authors: giachin g. Chem Sci. 2022 Aug 5;13(35):10406-10427. doi: 10.1039/d2sc00345g. eCollection 2022 Sep 14. Chem Sci. 2022. PMID: 36277622 Free PMC article.
42 results