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SLC7A8 coding for LAT2 is associated with early disease progression in osteosarcoma and transports doxorubicin.
Front Pharmacol. 2022 Nov 9;13:1042989. doi: 10.3389/fphar.2022.1042989. eCollection 2022.
Front Pharmacol. 2022.
PMID: 36438828
Free PMC article.
High-quality genotyping data from formalin-fixed, paraffin-embedded tissue on the drug metabolizing enzymes and transporters plus array.
Vos HI, van der Straaten T, Coenen MJ, Flucke U, te Loo DM, Guchelaar HJ.
Vos HI, et al.
J Mol Diagn. 2015 Jan;17(1):4-9. doi: 10.1016/j.jmoldx.2014.08.003.
J Mol Diagn. 2015.
PMID: 25528187
Free article.
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Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.
Hagleitner MM, Coenen MJ, Patino-Garcia A, de Bont ES, Gonzalez-Neira A, Vos HI, van Leeuwen FN, Gelderblom H, Hoogerbrugge PM, Guchelaar HJ, Te Loo MW.
Hagleitner MM, et al. Among authors: vos hi.
PLoS One. 2014 Dec 31;9(12):e115869. doi: 10.1371/journal.pone.0115869. eCollection 2014.
PLoS One. 2014.
PMID: 25551397
Free PMC article.
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A First Step toward Personalized Medicine in Osteosarcoma: Pharmacogenetics as Predictive Marker of Outcome after Chemotherapy-Based Treatment.
Hagleitner MM, Coenen MJ, Gelderblom H, Makkinje RR, Vos HI, de Bont ES, van der Graaf WT, Schreuder HW, Flucke U, van Leeuwen FN, Hoogerbrugge PM, Guchelaar HJ, te Loo DM.
Hagleitner MM, et al. Among authors: vos hi.
Clin Cancer Res. 2015 Aug 1;21(15):3436-41. doi: 10.1158/1078-0432.CCR-14-2638. Epub 2015 Mar 31.
Clin Cancer Res. 2015.
PMID: 25829401
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Replication of a genetic variant in ACYP2 associated with cisplatin-induced hearing loss in patients with osteosarcoma.
Vos HI, Guchelaar HJ, Gelderblom H, de Bont ES, Kremer LC, Naber AM, Hakobjan MH, van der Graaf WT, Coenen MJ, te Loo DM.
Vos HI, et al.
Pharmacogenet Genomics. 2016 May;26(5):243-7. doi: 10.1097/FPC.0000000000000212.
Pharmacogenet Genomics. 2016.
PMID: 26928270
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The role of pharmacogenetics in the treatment of osteosarcoma.
Vos HI, Coenen MJ, Guchelaar HJ, Te Loo DM.
Vos HI, et al.
Drug Discov Today. 2016 Nov;21(11):1775-1786. doi: 10.1016/j.drudis.2016.06.022. Epub 2016 Jun 25.
Drug Discov Today. 2016.
PMID: 27352631
Review.
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Histone deacetylase inhibitors enhance expression of NKG2D ligands in Ewing sarcoma and sensitize for natural killer cell-mediated cytolysis.
Berghuis D, Schilham MW, Vos HI, Santos SJ, Kloess S, Buddingh' EP, Egeler RM, Hogendoorn PC, Lankester AC.
Berghuis D, et al. Among authors: vos hi.
Clin Sarcoma Res. 2012 Feb 8;2(1):8. doi: 10.1186/2045-3329-2-8.
Clin Sarcoma Res. 2012.
PMID: 22587892
Free PMC article.
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