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Microbiological profile, preclinical pharmacokinetics and efficacy of CRS0393, a novel antimycobacterial agent targeting MmpL3.
Ochsner UA, De Groote MA, Jarvis TC, Liu H, Youmans T, Hoang T, Ribble W, Day J, Li W, Pearce C, Walz A, Panthi CM, Rimal B, Stevens CM, Zgurskaya HI, Jackson M, Ordway D, Gonzalez-Juarrero M, Sun X, Lamichhane G, Mason C. Ochsner UA, et al. Among authors: lamichhane g. Tuberculosis (Edinb). 2023 Jan;138:102288. doi: 10.1016/j.tube.2022.102288. Epub 2022 Nov 29. Tuberculosis (Edinb). 2023. PMID: 36470124 Free PMC article.
Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.
De Jager V, Gupte N, Nunes S, Barnes GL, van Wijk RC, Mostert J, Dorman SE, Abulfathi AA, Upton CM, Faraj A, Nuermberger EL, Lamichhane G, Svensson EM, Simonsson USH, Diacon AH, Dooley KE. De Jager V, et al. Among authors: lamichhane g. Am J Respir Crit Care Med. 2022 May 15;205(10):1228-1235. doi: 10.1164/rccm.202108-1976OC. Am J Respir Crit Care Med. 2022. PMID: 35258443 Free PMC article. Clinical Trial.
Drug resistance mechanisms and novel drug targets for tuberculosis therapy.
Islam MM, Hameed HMA, Mugweru J, Chhotaray C, Wang C, Tan Y, Liu J, Li X, Tan S, Ojima I, Yew WW, Nuermberger E, Lamichhane G, Zhang T. Islam MM, et al. Among authors: lamichhane g. J Genet Genomics. 2017 Jan 20;44(1):21-37. doi: 10.1016/j.jgg.2016.10.002. Epub 2016 Oct 11. J Genet Genomics. 2017. PMID: 28117224 Review.
Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.
Njire M, Wang N, Wang B, Tan Y, Cai X, Liu Y, Mugweru J, Guo J, Hameed HMA, Tan S, Liu J, Yew WW, Nuermberger E, Lamichhane G, Liu J, Zhang T. Njire M, et al. Among authors: lamichhane g. Antimicrob Agents Chemother. 2017 Jun 27;61(7):e00070-17. doi: 10.1128/AAC.00070-17. Print 2017 Jul. Antimicrob Agents Chemother. 2017. PMID: 28438933 Free PMC article.
Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins.
Kumar P, Chauhan V, Silva JRA, Lameira J, d'Andrea FB, Li SG, Ginell SL, Freundlich JS, Alves CN, Bailey S, Cohen KA, Lamichhane G. Kumar P, et al. Among authors: lamichhane g. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e00866-17. doi: 10.1128/AAC.00866-17. Print 2017 Oct. Antimicrob Agents Chemother. 2017. PMID: 28760902 Free PMC article.
111 results