Segal DJ - Search Results

1

Dr.Nod: computational framework for discovery of regulatory non-coding drivers in tissue-matched distal regulatory elements.

Tomkova M, Tomek J, Chow J, McPherson JD, Segal DJ, Hormozdiari F. Tomkova M, et al. Among authors: segal dj. Nucleic Acids Res. 2023 Feb 28;51(4):e23. doi: 10.1093/nar/gkac1251. Nucleic Acids Res. 2023. PMID: 36625266 Free PMC article.

2

Quantitative analysis of TALE-DNA interactions suggests polarity effects.

Meckler JF, Bhakta MS, Kim MS, Ovadia R, Habrian CH, Zykovich A, Yu A, Lockwood SH, Morbitzer R, Elsäesser J, Lahaye T, Segal DJ, Baldwin EP. Meckler JF, et al. Among authors: segal dj. Nucleic Acids Res. 2013 Apr;41(7):4118-28. doi: 10.1093/nar/gkt085. Epub 2013 Feb 13. Nucleic Acids Res. 2013. PMID: 23408851 Free PMC article.

3

Transcription activator like effector (TALE)-directed piggyBac transposition in human cells.

Owens JB, Mauro D, Stoytchev I, Bhakta MS, Kim MS, Segal DJ, Moisyadi S. Owens JB, et al. Among authors: segal dj. Nucleic Acids Res. 2013 Oct;41(19):9197-207. doi: 10.1093/nar/gkt677. Epub 2013 Aug 5. Nucleic Acids Res. 2013. PMID: 23921635 Free PMC article.

4

A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture.

O'Geen H, Henry IM, Bhakta MS, Meckler JF, Segal DJ. O'Geen H, et al. Among authors: segal dj. Nucleic Acids Res. 2015 Mar 31;43(6):3389-404. doi: 10.1093/nar/gkv137. Epub 2015 Feb 20. Nucleic Acids Res. 2015. PMID: 25712100 Free PMC article.

5

Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells.

Tak YG, Hung Y, Yao L, Grimmer MR, Do A, Bhakta MS, O'Geen H, Segal DJ, Farnham PJ. Tak YG, et al. Among authors: segal dj. Nucleic Acids Res. 2016 May 19;44(9):4123-33. doi: 10.1093/nar/gkv1530. Epub 2016 Jan 6. Nucleic Acids Res. 2016. PMID: 26743005 Free PMC article.

6

dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.

O'Geen H, Ren C, Nicolet CM, Perez AA, Halmai J, Le VM, Mackay JP, Farnham PJ, Segal DJ. O'Geen H, et al. Among authors: segal dj. Nucleic Acids Res. 2017 Sep 29;45(17):9901-9916. doi: 10.1093/nar/gkx578. Nucleic Acids Res. 2017. PMID: 28973434 Free PMC article.

7

Artificial escape from XCI by DNA methylation editing of the CDKL5 gene.

Halmai JANM, Deng P, Gonzalez CE, Coggins NB, Cameron D, Carter JL, Buchanan FKB, Waldo JJ, Lock SR, Anderson JD, O'Geen H, Segal DJ, Nolta J, Fink KD. Halmai JANM, et al. Among authors: segal dj. Nucleic Acids Res. 2020 Mar 18;48(5):2372-2387. doi: 10.1093/nar/gkz1214. Nucleic Acids Res. 2020. PMID: 31925439 Free PMC article.

8

Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3 and Ezh2-dCas9 + DNMT3 hit-and-run epigenome editing.

O'Geen H, Tomkova M, Combs JA, Tilley EK, Segal DJ. O'Geen H, et al. Among authors: segal dj. Nucleic Acids Res. 2022 Apr 8;50(6):3239-3253. doi: 10.1093/nar/gkac123. Nucleic Acids Res. 2022. PMID: 35234927 Free PMC article.

9

Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons.

Fugon OJG, Sharifi O, Heath NG, Soto DC, Gomez JA, Yasui DH, Mendiola AJP, O'Geen H, Beitnere U, Tomkova M, Haghani V, Dillon G, Segal DJ, LaSalle J. Fugon OJG, et al. Among authors: segal dj. bioRxiv [Preprint]. 2024 Mar 29:2024.03.26.586689. doi: 10.1101/2024.03.26.586689. bioRxiv. 2024. PMID: 38586056 Free PMC article. Preprint.

10

Bind-n-Seq: high-throughput analysis of in vitro protein-DNA interactions using massively parallel sequencing.

Zykovich A, Korf I, Segal DJ. Zykovich A, et al. Among authors: segal dj. Nucleic Acids Res. 2009 Dec;37(22):e151. doi: 10.1093/nar/gkp802. Nucleic Acids Res. 2009. PMID: 19843614 Free PMC article.

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