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Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity.
Morla S, Ravikumar O, O'Hara C, Boothello R, Vera A, Abdelfadiel EI, Fayyad R, Afosah DK, Sharon C, Fernandez L, Shah SA, Patel BB, Desai UR. Morla S, et al. Among authors: boothello r. J Med Chem. 2023 Jan 26;66(2):1321-1338. doi: 10.1021/acs.jmedchem.2c01511. Epub 2023 Jan 12. J Med Chem. 2023. PMID: 36634271 Free PMC article.
Glycan Modulation of Insulin-like Growth Factor-1 Receptor.
Boothello RS, Sankaranarayanan NV, Sistla JC, Nagarajan B, Sharon C, Chittum JE, Niyaz RY, Roy S, Nandi A, O'Hara CP, Gangji RN, Afosah DK, Ongolu R, Patel BB, Desai UR. Boothello RS, et al. Angew Chem Int Ed Engl. 2022 Dec 5;61(49):e202211320. doi: 10.1002/anie.202211320. Epub 2022 Nov 9. Angew Chem Int Ed Engl. 2022. PMID: 36205924 Free PMC article.
Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress.
Omar AM, El-Araby ME, Abdelghany TM, Safo MK, Ahmed MH, Boothello R, Patel BB, Abdel-Bakky MS, Malebari AM, Ahmed HEA, Elhaggar RS. Omar AM, et al. Among authors: boothello r. Bioorg Chem. 2020 Aug;101:103953. doi: 10.1016/j.bioorg.2020.103953. Epub 2020 May 25. Bioorg Chem. 2020. PMID: 32474179
A Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II.
Sankarayanarayanan NV, Strebel TR, Boothello RS, Sheerin K, Raghuraman A, Sallas F, Mosier PD, Watermeyer ND, Oscarson S, Desai UR. Sankarayanarayanan NV, et al. Among authors: boothello rs. Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2312-2317. doi: 10.1002/anie.201609541. Epub 2017 Jan 26. Angew Chem Int Ed Engl. 2017. PMID: 28124818 Free PMC article.
15 results