Fontenla JÁ - Search Results

1

8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies.

Matos MJ, Novo P, Mayán L, Torres I, Uriarte E, Yáñez M, Fontenla JÁ, Ortuso F, Alcaro S, Procopio F, Rodríguez-Franco MI, Val C, Loza MI, Brea J, Borges F, Viña D. Matos MJ, et al. Among authors: fontenla ja. Eur J Med Chem. 2023 Feb 15;248:115091. doi: 10.1016/j.ejmech.2023.115091. Epub 2023 Jan 7. Eur J Med Chem. 2023. PMID: 36638711 Free article.

2

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study.

Matos MJ, Vilar S, Gonzalez-Franco RM, Uriarte E, Santana L, Friedman C, Tatonetti NP, Viña D, Fontenla JA. Matos MJ, et al. Among authors: fontenla ja. Eur J Med Chem. 2013 May;63:151-61. doi: 10.1016/j.ejmech.2013.02.009. Epub 2013 Feb 16. Eur J Med Chem. 2013. PMID: 23474901

3

Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases.

Matos MJ, Janeiro P, González Franco RM, Vilar S, Tatonetti NP, Santana L, Uriarte E, Borges F, Fontenla JA, Viña D. Matos MJ, et al. Among authors: fontenla ja. Future Med Chem. 2014 Mar;6(4):371-83. doi: 10.4155/fmc.14.9. Future Med Chem. 2014. PMID: 24635520

4

Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies.

Rodríguez-Enríquez F, Viña D, Uriarte E, Fontenla JA, Matos MJ. Rodríguez-Enríquez F, et al. Among authors: fontenla ja. Bioorg Chem. 2020 Aug;101:103986. doi: 10.1016/j.bioorg.2020.103986. Epub 2020 Jun 2. Bioorg Chem. 2020. PMID: 32569895

5

Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian drug.

Pflüger P, Pereira P, Loza MI, Brea J, Viña D, Kumar A, Fontenla JA. Pflüger P, et al. Among authors: fontenla ja. Eur J Pharmacol. 2021 Sep 5;906:174276. doi: 10.1016/j.ejphar.2021.174276. Epub 2021 Jun 23. Eur J Pharmacol. 2021. PMID: 34174267 Free article.

6

Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: synthesis and determination of affinities at D(2), 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.

Masaguer CF, Raviña E, Fontenla JA, Brea J, Tristán H, Loza MI. Masaguer CF, et al. Among authors: fontenla ja. Eur J Med Chem. 2000 Jan;35(1):83-95. doi: 10.1016/s0223-5234(00)00109-4. Eur J Med Chem. 2000. PMID: 10733606

7

Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.

López MC, Fontenla JA, Uriarte E, Santana L, Sobarzo-Sánchez E. López MC, et al. Among authors: fontenla ja. Curr Top Med Chem. 2014;14(2):234-8. doi: 10.2174/1568026613666131213162753. Curr Top Med Chem. 2014. PMID: 24359197

8

MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis, in vitro study, and docking calculations.

Delogu GL, Pintus F, Mayán L, Matos MJ, Vilar S, Munín J, Fontenla JA, Hripcsak G, Borges F, Viña D. Delogu GL, et al. Among authors: fontenla ja. Medchemcomm. 2017 Jul 7;8(9):1788-1796. doi: 10.1039/c7md00311k. eCollection 2017 Sep 1. Medchemcomm. 2017. PMID: 30108888 Free PMC article.

9

Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical antipsychotics.

Raviña E, Negreira J, Cid J, Masaguer CF, Rosa E, Rivas ME, Fontenla JA, Loza MI, Tristán H, Cadavid MI, Sanz F, Lozoya E, Carotti A, Carrieri A. Raviña E, et al. Among authors: fontenla ja. J Med Chem. 1999 Jul 29;42(15):2774-97. doi: 10.1021/jm981094e. J Med Chem. 1999. PMID: 10425088

10

New arylpiperazine derivatives with high affinity for alpha1A, D2 and 5-HT2A receptors.

González-Gómez JC, Santana L, Uriarte E, Brea J, Villazón M, Loza MI, De Luca M, Rivas ME, Montenegro GY, Fontenla JA. González-Gómez JC, et al. Among authors: fontenla ja. Bioorg Med Chem Lett. 2003 Jan 20;13(2):175-8. doi: 10.1016/s0960-894x(02)00933-2. Bioorg Med Chem Lett. 2003. PMID: 12482418

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