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Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.
Saijo S, Ikeda S, Yamabe K, Kakuta S, Ishigame H, Akitsu A, Fujikado N, Kusaka T, Kubo S, Chung SH, Komatsu R, Miura N, Adachi Y, Ohno N, Shibuya K, Yamamoto N, Kawakami K, Yamasaki S, Saito T, Akira S, Iwakura Y. Saijo S, et al. Immunity. 2010 May 28;32(5):681-91. doi: 10.1016/j.immuni.2010.05.001. Epub 2010 May 20. Immunity. 2010. PMID: 20493731 Free article.
STING manifests self DNA-dependent inflammatory disease.
Ahn J, Gutman D, Saijo S, Barber GN. Ahn J, et al. Among authors: saijo s. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19386-91. doi: 10.1073/pnas.1215006109. Epub 2012 Nov 6. Proc Natl Acad Sci U S A. 2012. PMID: 23132945 Free PMC article.
Dectin-2 is a direct receptor for mannose-capped lipoarabinomannan of mycobacteria.
Yonekawa A, Saijo S, Hoshino Y, Miyake Y, Ishikawa E, Suzukawa M, Inoue H, Tanaka M, Yoneyama M, Oh-Hora M, Akashi K, Yamasaki S. Yonekawa A, et al. Among authors: saijo s. Immunity. 2014 Sep 18;41(3):402-413. doi: 10.1016/j.immuni.2014.08.005. Epub 2014 Aug 28. Immunity. 2014. PMID: 25176311 Free article.
Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans.
Nakamura Y, Sato K, Yamamoto H, Matsumura K, Matsumoto I, Nomura T, Miyasaka T, Ishii K, Kanno E, Tachi M, Yamasaki S, Saijo S, Iwakura Y, Kawakami K. Nakamura Y, et al. Among authors: saijo s. Infect Immun. 2015 Feb;83(2):671-81. doi: 10.1128/IAI.02835-14. Epub 2014 Nov 24. Infect Immun. 2015. PMID: 25422263 Free PMC article.
CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis.
Murayama MA, Kakuta S, Inoue A, Umeda N, Yonezawa T, Maruhashi T, Tateishi K, Ishigame H, Yabe R, Ikeda S, Seno A, Chi HH, Hashiguchi Y, Kurata R, Tada T, Kubo S, Sato N, Liu Y, Hattori M, Saijo S, Matsushita M, Fujita T, Sumida T, Iwakura Y. Murayama MA, et al. Among authors: saijo s. Nat Commun. 2015 Sep 25;6:8483. doi: 10.1038/ncomms9483. Nat Commun. 2015. PMID: 26404464 Free PMC article.
223 results