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A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Altea-Manzano P, Doglioni G, Liu Y, Cuadros AM, Nolan E, Fernández-García J, Wu Q, Planque M, Laue KJ, Cidre-Aranaz F, Liu XZ, Marin-Bejar O, Van Elsen J, Vermeire I, Broekaert D, Demeyer S, Spotbeen X, Idkowiak J, Montagne A, Demicco M, Alkan HF, Rabas N, Riera-Domingo C, Richard F, Geukens T, De Schepper M, Leduc S, Hatse S, Lambrechts Y, Kay EJ, Lilla S, Alekseenko A, Geldhof V, Boeckx B, de la Calle Arregui C, Floris G, Swinnen JV, Marine JC, Lambrechts D, Pelechano V, Mazzone M, Zanivan S, Cools J, Wildiers H, Baud V, Grünewald TGP, Ben-David U, Desmedt C, Malanchi I, Fendt SM. Altea-Manzano P, et al. Among authors: desmedt c. Nat Cancer. 2023 Mar;4(3):344-364. doi: 10.1038/s43018-023-00513-2. Epub 2023 Feb 2. Nat Cancer. 2023. PMID: 36732635 Free PMC article.
Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations.
Brown D, Smeets D, Székely B, Larsimont D, Szász AM, Adnet PY, Rothé F, Rouas G, Nagy ZI, Faragó Z, Tőkés AM, Dank M, Szentmártoni G, Udvarhelyi N, Zoppoli G, Pusztai L, Piccart M, Kulka J, Lambrechts D, Sotiriou C, Desmedt C. Brown D, et al. Among authors: desmedt c. Nat Commun. 2017 Apr 20;8:14944. doi: 10.1038/ncomms14944. Nat Commun. 2017. PMID: 28429735 Free PMC article.
Tumor characteristics and outcome by androgen receptor expression in triple-negative breast cancer patients treated with neo-adjuvant chemotherapy.
Jongen L, Floris G, Wildiers H, Claessens F, Richard F, Laenen A, Desmedt C, Ardui J, Punie K, Smeets A, Berteloot P, Vergote I, Neven P. Jongen L, et al. Among authors: desmedt c. Breast Cancer Res Treat. 2019 Aug;176(3):699-708. doi: 10.1007/s10549-019-05252-6. Epub 2019 May 20. Breast Cancer Res Treat. 2019. PMID: 31106385
Phylogenetic reconstruction of breast cancer reveals two routes of metastatic dissemination associated with distinct clinical outcome.
Venet D, Fimereli D, Rothé F, Boeckx B, Maetens M, Majjaj S, Rouas G, Capra M, Bonizzi G, Contaldo F, Galant C, Piccart M, Pruneri G, Larsimont D, Lambrechts D, Desmedt C, Sotiriou C. Venet D, et al. Among authors: desmedt c. EBioMedicine. 2020 Jun;56:102793. doi: 10.1016/j.ebiom.2020.102793. Epub 2020 Jun 5. EBioMedicine. 2020. PMID: 32512508 Free PMC article.
Assessment of stromal tumor infiltrating lymphocytes and immunohistochemical features in invasive micropapillary breast carcinoma with long-term outcomes.
Deman F, Punie K, Laenen A, Neven P, Oldenburger E, Smeets A, Nevelsteen I, Van Ongeval C, Baten A, Faes T, Christiaens M, Janssen H, Weltens C, Desmedt C, Wildiers H, Floris G. Deman F, et al. Among authors: desmedt c. Breast Cancer Res Treat. 2020 Dec;184(3):985-998. doi: 10.1007/s10549-020-05913-x. Epub 2020 Sep 12. Breast Cancer Res Treat. 2020. PMID: 32920743
Characterization of Stromal Tumor-infiltrating Lymphocytes and Genomic Alterations in Metastatic Lobular Breast Cancer.
Richard F, Majjaj S, Venet D, Rothé F, Pingitore J, Boeckx B, Marchio C, Clatot F, Bertucci F, Mariani O, Galant C, Eynden GVD, Salgado R, Biganzoli E, Lambrechts D, Vincent-Salomon A, Pruneri G, Larsimont D, Sotiriou C, Desmedt C. Richard F, et al. Among authors: desmedt c. Clin Cancer Res. 2020 Dec 1;26(23):6254-6265. doi: 10.1158/1078-0432.CCR-20-2268. Epub 2020 Sep 17. Clin Cancer Res. 2020. PMID: 32943456
Digital analysis of distant and cancer-associated mammary adipocytes.
Isnaldi E, Richard F, De Schepper M, Vincent D, Leduc S, Maetens M, Geukens T, Floris G, Rouas G, Cardoso F, Sotiriou C, Zoppoli G, Larsimont D, Biganzoli E, Desmedt C. Isnaldi E, et al. Among authors: desmedt c. Breast. 2020 Dec;54:179-186. doi: 10.1016/j.breast.2020.10.004. Epub 2020 Oct 16. Breast. 2020. PMID: 33120083 Free PMC article.
Body Mass Index and Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer.
Floris G, Richard F, Hamy AS, Jongen L, Wildiers H, Ardui J, Punie K, Smeets A, Berteloot P, Vergote I, De Croze D, Meseure D, Salomon A, Laé M, Reyal F, Biganzoli E, Neven P, Desmedt C. Floris G, et al. Among authors: desmedt c. J Natl Cancer Inst. 2021 Feb 1;113(2):146-153. doi: 10.1093/jnci/djaa090. J Natl Cancer Inst. 2021. PMID: 33152071 Free PMC article.
232 results