Dahab MA - Search Results

1

Synthesis of 1,2,4-Triazinones Exploiting the Reactivity of Diazadiene and N-Isocyanate Intermediates.

Vuillermet F, Dahab MA, Abdelhamid D, Polat DE, Gill MA, Beauchemin AM. Vuillermet F, et al. Among authors: dahab ma. J Org Chem. 2023 Feb 17;88(4):2095-2102. doi: 10.1021/acs.joc.2c02494. Epub 2023 Feb 7. J Org Chem. 2023. PMID: 36749643

2

Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers.

Eissa IH, El-Haggar R, Dahab MA, Ahmed MF, Mahdy HA, Alsantali RI, Elwan A, Masurier N, Fatahala SS. Eissa IH, et al. Among authors: dahab ma. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1587-1599. doi: 10.1080/14756366.2022.2081844. J Enzyme Inhib Med Chem. 2022. PMID: 35637622 Free PMC article.

3

Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation.

Elwan A, Abdallah AE, Mahdy HA, Dahab MA, Taghour MS, Elkaeed EB, Mehany ABM, Nabeeh A, Adel M, Alsfouk AA, Elkady H, Eissa IH. Elwan A, et al. Among authors: dahab ma. Molecules. 2022 Aug 8;27(15):5047. doi: 10.3390/molecules27155047. Molecules. 2022. PMID: 35956997 Free PMC article.

4

New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies.

Elkaeed EB, Taghour MS, Mahdy HA, Eldehna WM, El-Deeb NM, Kenawy AM, A Alsfouk B, Dahab MA, Metwaly AM, Eissa IH, El-Zahabi MA. Elkaeed EB, et al. Among authors: dahab ma. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2191-2205. doi: 10.1080/14756366.2022.2110869. J Enzyme Inhib Med Chem. 2022. PMID: 35975321 Free PMC article.

5

Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies.

Alsaif NA, Taghour MS, Alanazi MM, Obaidullah AJ, Alanazi WA, Alasmari A, Albassam H, Dahab MA, Mahdy HA. Alsaif NA, et al. Among authors: dahab ma. Bioorg Med Chem. 2021 Sep 15;46:116384. doi: 10.1016/j.bmc.2021.116384. Epub 2021 Aug 28. Bioorg Med Chem. 2021. PMID: 34479065

6

New quinoxaline-based VEGFR-2 inhibitors: design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies.

Alanazi MM, Elkady H, Alsaif NA, Obaidullah AJ, Alkahtani HM, Alanazi MM, Alharbi MA, Eissa IH, Dahab MA. Alanazi MM, et al. Among authors: dahab ma. RSC Adv. 2021 Oct 12;11(48):30315-30328. doi: 10.1039/d1ra05925d. eCollection 2021 Sep 6. RSC Adv. 2021. PMID: 35493991 Free PMC article.

7

Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.

Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM. Eissa IH, et al. Among authors: dahab ma. Bioorg Chem. 2021 Jul;112:104965. doi: 10.1016/j.bioorg.2021.104965. Epub 2021 May 5. Bioorg Chem. 2021. PMID: 34020238

8

New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations.

Mahdy HA, Elkady H, Taghour MS, Elwan A, Dahab MA, Elkady MA, Elsakka EG, Elkaeed EB, Alsfouk BA, Ibrahim IM, Eissa IH, Metwaly AM. Mahdy HA, et al. Among authors: dahab ma. Future Med Chem. 2023 Jul;15(14):1233-1250. doi: 10.4155/fmc-2023-0089. Epub 2023 Jul 19. Future Med Chem. 2023. PMID: 37466069

9

Synthesis, biological evaluation and computer-aided discovery of new thiazolidine-2,4-dione derivatives as potential antitumor VEGFR-2 inhibitors.

Elkady H, El-Dardir OA, Elwan A, Taghour MS, Mahdy HA, Dahab MA, Elkaeed EB, Alsfouk BA, Ibrahim IM, Husein DZ, Hafez EE, Darwish AMG, Metwaly AM, Eissa IH. Elkady H, et al. Among authors: dahab ma. RSC Adv. 2023 Sep 19;13(40):27801-27827. doi: 10.1039/d3ra05689a. eCollection 2023 Sep 18. RSC Adv. 2023. PMID: 37731835 Free PMC article.

10

Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor.

Al-Karmalawy AA, Dahab MA, Metwaly AM, Elhady SS, Elkaeed EB, Eissa IH, Darwish KM. Al-Karmalawy AA, et al. Among authors: dahab ma. Front Chem. 2021 May 4;9:661230. doi: 10.3389/fchem.2021.661230. eCollection 2021. Front Chem. 2021. PMID: 34017819 Free PMC article.

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