Vertegaal ACO - Search Results

1

Inhibition of SUMOylation enhances DNA hypomethylating drug efficacy to reduce outgrowth of hematopoietic malignancies.

Kroonen JS, de Graaf IJ, Kumar S, Remst DFG, Wouters AK, Heemskerk MHM, Vertegaal ACO. Kroonen JS, et al. Among authors: vertegaal aco. Leukemia. 2023 Apr;37(4):864-876. doi: 10.1038/s41375-023-01838-8. Epub 2023 Feb 15. Leukemia. 2023. PMID: 36792656 Free PMC article.

2

The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization.

Scheper GC, Parra JL, Wilson M, Van Kollenburg B, Vertegaal AC, Han ZG, Proud CG. Scheper GC, et al. Mol Cell Biol. 2003 Aug;23(16):5692-705. doi: 10.1128/MCB.23.16.5692-5705.2003. Mol Cell Biol. 2003. PMID: 12897141 Free PMC article.

3

A proteomic study of SUMO-2 target proteins.

Vertegaal AC, Ogg SC, Jaffray E, Rodriguez MS, Hay RT, Andersen JS, Mann M, Lamond AI. Vertegaal AC, et al. J Biol Chem. 2004 Aug 6;279(32):33791-8. doi: 10.1074/jbc.M404201200. Epub 2004 Jun 2. J Biol Chem. 2004. PMID: 15175327 Free article.

4

Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif.

Matic I, Schimmel J, Hendriks IA, van Santen MA, van de Rijke F, van Dam H, Gnad F, Mann M, Vertegaal AC. Matic I, et al. Mol Cell. 2010 Aug 27;39(4):641-52. doi: 10.1016/j.molcel.2010.07.026. Mol Cell. 2010. PMID: 20797634 Free article.

5

The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity.

Buijs A, van Rompaey L, Molijn AC, Davis JN, Vertegaal AC, Potter MD, Adams C, van Baal S, Zwarthoff EC, Roussel MF, Grosveld GC. Buijs A, et al. Mol Cell Biol. 2000 Dec;20(24):9281-93. doi: 10.1128/MCB.20.24.9281-9293.2000. Mol Cell Biol. 2000. PMID: 11094079 Free PMC article.

6

Identification of SUMO target proteins by quantitative proteomics.

Andersen JS, Matic I, Vertegaal AC. Andersen JS, et al. Methods Mol Biol. 2009;497:19-31. doi: 10.1007/978-1-59745-566-4_2. Methods Mol Biol. 2009. PMID: 19107408 Review.

7

RNF4 is required for DNA double-strand break repair in vivo.

Vyas R, Kumar R, Clermont F, Helfricht A, Kalev P, Sotiropoulou P, Hendriks IA, Radaelli E, Hochepied T, Blanpain C, Sablina A, van Attikum H, Olsen JV, Jochemsen AG, Vertegaal AC, Marine JC. Vyas R, et al. Cell Death Differ. 2013 Mar;20(3):490-502. doi: 10.1038/cdd.2012.145. Epub 2012 Nov 30. Cell Death Differ. 2013. PMID: 23197296 Free PMC article.

8

The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation.

Liebelt F, Jansen NS, Kumar S, Gracheva E, Claessens LA, Verlaan-de Vries M, Willemstein E, Vertegaal ACO. Liebelt F, et al. Among authors: vertegaal aco. Nat Commun. 2019 Sep 4;10(1):3987. doi: 10.1038/s41467-019-11773-x. Nat Commun. 2019. PMID: 31485003 Free PMC article.

9

Targeting SUMO Signaling to Wrestle Cancer.

Kroonen JS, Vertegaal ACO. Kroonen JS, et al. Among authors: vertegaal aco. Trends Cancer. 2021 Jun;7(6):496-510. doi: 10.1016/j.trecan.2020.11.009. Epub 2020 Dec 20. Trends Cancer. 2021. PMID: 33353838 Free article. Review.

10

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation.

Yatskevich S, Kroonen JS, Alfieri C, Tischer T, Howes AC, Clijsters L, Yang J, Zhang Z, Yan K, Vertegaal ACO, Barford D. Yatskevich S, et al. Among authors: vertegaal aco. Cell Rep. 2021 Mar 30;34(13):108929. doi: 10.1016/j.celrep.2021.108929. Cell Rep. 2021. PMID: 33789095 Free PMC article.

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