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Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells.
Cell Chem Biol. 2023 Mar 16;30(3):321-336.e6. doi: 10.1016/j.chembiol.2023.02.006. Epub 2023 Mar 7.
Cell Chem Biol. 2023.
PMID: 36889310
Free PMC article.
Cysteine reactivity across the subcellular universe.
Bak DW, Bechtel TJ, Falco JA, Weerapana E.
Bak DW, et al. Among authors: falco ja.
Curr Opin Chem Biol. 2019 Feb;48:96-105. doi: 10.1016/j.cbpa.2018.11.002. Epub 2018 Nov 30.
Curr Opin Chem Biol. 2019.
PMID: 30508703
Free PMC article.
Review.
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Generation of Recombinant Mammalian Selenoproteins through Genetic Code Expansion with Photocaged Selenocysteine.
Peeler JC, Falco JA, Kelemen RE, Abo M, Chartier BV, Edinger LC, Chen J, Chatterjee A, Weerapana E.
Peeler JC, et al. Among authors: falco ja.
ACS Chem Biol. 2020 Jun 19;15(6):1535-1540. doi: 10.1021/acschembio.0c00147. Epub 2020 May 5.
ACS Chem Biol. 2020.
PMID: 32330002
Free PMC article.
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Ferlins and TgDOC2 in Toxoplasma Microneme, Rhoptry and Dense Granule Secretion.
Tagoe DNA, Drozda AA, Falco JA, Bechtel TJ, Weerapana E, Gubbels MJ.
Tagoe DNA, et al. Among authors: falco ja.
Life (Basel). 2021 Mar 9;11(3):217. doi: 10.3390/life11030217.
Life (Basel). 2021.
PMID: 33803212
Free PMC article.
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CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery.
Benns HJ, Storch M, Falco JA, Fisher FR, Tamaki F, Alves E, Wincott CJ, Milne R, Wiedemar N, Craven G, Baragaña B, Wyllie S, Baum J, Baldwin GS, Weerapana E, Tate EW, Child MA.
Benns HJ, et al. Among authors: falco ja.
Nat Microbiol. 2022 Nov;7(11):1891-1905. doi: 10.1038/s41564-022-01249-y. Epub 2022 Oct 20.
Nat Microbiol. 2022.
PMID: 36266336
Free PMC article.
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Chemoproteomics Reveals Disruption of Metal Homeostasis and Metalloproteins by the Antibiotic Holomycin.
Chan AN, Chen X, Falco JA, Bak DW, Weerapana E, Li B.
Chan AN, et al. Among authors: falco ja.
ACS Chem Biol. 2023 Sep 15;18(9):1909-1914. doi: 10.1021/acschembio.3c00360. Epub 2023 Aug 10.
ACS Chem Biol. 2023.
PMID: 37561838
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Identification of Protein Targets of S-Nitroso-Coenzyme A-Mediated S-Nitrosation Using Chemoproteomics.
Falco JA, Wynia-Smith SL, McCoy J, Smith BC, Weerapana E.
Falco JA, et al.
ACS Chem Biol. 2024 Jan 19;19(1):193-207. doi: 10.1021/acschembio.3c00654. Epub 2023 Dec 30.
ACS Chem Biol. 2024.
PMID: 38159293
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