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Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease.
Sci Rep. 2023 Apr 6;13(1):5665. doi: 10.1038/s41598-023-32971-0.
Sci Rep. 2023.
PMID: 37024714
Free PMC article.
Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C.
Kavetsky L, Green KK, Boyle BR, Yousufzai FAK, Padron ZM, Melli SE, Kuhnel VL, Jackson HM, Blanco RE, Howell GR, Soto I.
Kavetsky L, et al. Among authors: melli se.
Sci Rep. 2019 Oct 11;9(1):14722. doi: 10.1038/s41598-019-51246-1.
Sci Rep. 2019.
PMID: 31605022
Free PMC article.
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NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann-Pick disease type C.
Boyle BR, Melli SE, Altreche RS, Padron ZM, Yousufzai FAK, Kim S, Vasquez MD, Carone DM, Carone BR, Soto I.
Boyle BR, et al. Among authors: melli se.
Development. 2020 Aug 3;147(21):dev189019. doi: 10.1242/dev.189019.
Development. 2020.
PMID: 32611604
Free PMC article.
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