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Intranasal soluble ACE2 improves survival and prevents brain SARS-CoV-2 infection.
Hassler L, Wysocki J, Ahrendsen JT, Ye M, Gelarden I, Nicolaescu V, Tomatsidou A, Gula H, Cianfarini C, Forster P, Khurram N, Singer BD, Randall G, Missiakas D, Henkin J, Batlle D. Hassler L, et al. Life Sci Alliance. 2023 Apr 11;6(7):e202301969. doi: 10.26508/lsa.202301969. Print 2023 Jul. Life Sci Alliance. 2023. PMID: 37041017 Free PMC article.
A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 Infection.
Hassler L, Wysocki J, Gelarden I, Sharma I, Tomatsidou A, Ye M, Gula H, Nicoleascu V, Randall G, Pshenychnyi S, Khurram N, Kanwar Y, Missiakas D, Henkin J, Yeldandi A, Batlle D. Hassler L, et al. J Am Soc Nephrol. 2022 Jul;33(7):1293-1307. doi: 10.1681/ASN.2021091209. Epub 2022 Mar 2. J Am Soc Nephrol. 2022. PMID: 35236774 Free PMC article.
Kidney Angiotensin in Cardiovascular Disease: Formation and Drug Targeting.
Lin H, Geurts F, Hassler L, Batlle D, Mirabito Colafella KM, Denton KM, Zhuo JL, Li XC, Ramkumar N, Koizumi M, Matsusaka T, Nishiyama A, Hoogduijn MJ, Hoorn EJ, Danser AHJ. Lin H, et al. Among authors: hassler l. Pharmacol Rev. 2022 Jul;74(3):462-505. doi: 10.1124/pharmrev.120.000236. Pharmacol Rev. 2022. PMID: 35710133 Free PMC article. Review.
Superiority of intranasal over systemic administration of bioengineered soluble ACE2 for survival and brain protection against SARS-CoV-2 infection.
Hassler L, Wysocki J, Ahrendsen JT, Ye M, Gelarden I, Nicolaescu V, Tomatsidou A, Gula H, Cianfarini C, Khurram N, Kanwar Y, Singer BD, Randall G, Missiakas D, Henkin J, Batlle D. Hassler L, et al. bioRxiv [Preprint]. 2022 Dec 6:2022.12.05.519032. doi: 10.1101/2022.12.05.519032. bioRxiv. 2022. PMID: 36523403 Free PMC article. Preprint.
32 results