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Intranasal soluble ACE2 improves survival and prevents brain SARS-CoV-2 infection.
Hassler L, Wysocki J, Ahrendsen JT, Ye M, Gelarden I, Nicolaescu V, Tomatsidou A, Gula H, Cianfarini C, Forster P, Khurram N, Singer BD, Randall G, Missiakas D, Henkin J, Batlle D. Hassler L, et al. Among authors: khurram n. Life Sci Alliance. 2023 Apr 11;6(7):e202301969. doi: 10.26508/lsa.202301969. Print 2023 Jul. Life Sci Alliance. 2023. PMID: 37041017 Free PMC article.
A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 Infection.
Hassler L, Wysocki J, Gelarden I, Sharma I, Tomatsidou A, Ye M, Gula H, Nicoleascu V, Randall G, Pshenychnyi S, Khurram N, Kanwar Y, Missiakas D, Henkin J, Yeldandi A, Batlle D. Hassler L, et al. Among authors: khurram n. J Am Soc Nephrol. 2022 Jul;33(7):1293-1307. doi: 10.1681/ASN.2021091209. Epub 2022 Mar 2. J Am Soc Nephrol. 2022. PMID: 35236774 Free PMC article.
Alpha-defensins: risk factor for thrombosis in COVID-19 infection.
Abdeen S, Bdeir K, Abu-Fanne R, Maraga E, Higazi M, Khurram N, Feldman M, Deshpande C, Litzky LA, Heyman SN, Montone KT, Cines DB, Higazi AA. Abdeen S, et al. Among authors: khurram n. Br J Haematol. 2021 Jul;194(1):44-52. doi: 10.1111/bjh.17503. Epub 2021 May 30. Br J Haematol. 2021. PMID: 34053084 Free PMC article. Clinical Trial.
IL-1β-dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction.
Yang W, Cerier EJ, Núñez-Santana FL, Wu Q, Yan Y, Kurihara C, Liu X, Yeldandi A, Khurram N, Avella-Patino D, Sun H, Budinger GRS, Kreisel D, Mohanakumar T, Lecuona E, Bharat A. Yang W, et al. Among authors: khurram n. J Clin Invest. 2022 Oct 17;132(20):e157975. doi: 10.1172/JCI157975. J Clin Invest. 2022. PMID: 36250462 Free PMC article.
Banff 2022 Liver Group Meeting report: Monitoring long-term allograft health.
Bellamy COC, O'Leary JG, Adeyi O, Baddour N, Batal I, Bucuvalas J, Del Bello A, El Hag M, El-Monayeri M, Farris AB 3rd, Feng S, Fiel MI, Fischer SE, Fung J, Grzyb K, Guimei M, Haga H, Hart J, Jackson AM, Jaeckel E, Khurram NA, Knechtle SJ, Lesniak D, Levitsky J, McCaughan G, McKenzie C, Mescoli C, Miquel R, Minervini MI, Nasser IA, Neil D, O'Neil MF, Pappo O, Randhawa P, Ruiz P, Fueyo AS, Schady D, Schiano T, Sebagh M, Smith M, Stevenson HL, Taner T, Taubert R, Thung S, Trunecka P, Wang HL, Wood-Trageser M, Yilmaz F, Zen Y, Zeevi A, Demetris AJ. Bellamy COC, et al. Among authors: khurram na. Am J Transplant. 2024 Mar 9:S1600-6135(24)00204-1. doi: 10.1016/j.ajt.2024.03.008. Online ahead of print. Am J Transplant. 2024. PMID: 38461883 Free article.
Superiority of intranasal over systemic administration of bioengineered soluble ACE2 for survival and brain protection against SARS-CoV-2 infection.
Hassler L, Wysocki J, Ahrendsen JT, Ye M, Gelarden I, Nicolaescu V, Tomatsidou A, Gula H, Cianfarini C, Khurram N, Kanwar Y, Singer BD, Randall G, Missiakas D, Henkin J, Batlle D. Hassler L, et al. Among authors: khurram n. bioRxiv [Preprint]. 2022 Dec 6:2022.12.05.519032. doi: 10.1101/2022.12.05.519032. bioRxiv. 2022. PMID: 36523403 Free PMC article. Preprint.
21 results