Marzio A - Search Results

1

FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors.

Nguyen-Dien GT, Kozul KL, Cui Y, Townsend B, Kulkarni PG, Ooi SS, Marzio A, Carrodus N, Zuryn S, Pagano M, Parton RG, Lazarou M, Millard SS, Taylor RW, Collins BM, Jones MJ, Pagan JK. Nguyen-Dien GT, et al. Among authors: marzio a. EMBO J. 2023 Jul 3;42(13):e112767. doi: 10.15252/embj.2022112767. Epub 2023 May 10. EMBO J. 2023. PMID: 37161784 Free PMC article.

2

Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.

Pagan JK, Marzio A, Jones MJ, Saraf A, Jallepalli PV, Florens L, Washburn MP, Pagano M. Pagan JK, et al. Among authors: marzio a. Nat Cell Biol. 2015 Jan;17(1):31-43. doi: 10.1038/ncb3076. Epub 2014 Dec 15. Nat Cell Biol. 2015. PMID: 25503564 Free PMC article.

3

GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK.

Pae J, Cinalli RM, Marzio A, Pagano M, Lehmann R. Pae J, et al. Among authors: marzio a. Dev Cell. 2017 Jul 24;42(2):130-142.e7. doi: 10.1016/j.devcel.2017.06.022. Dev Cell. 2017. PMID: 28743001 Free PMC article.

4

The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers.

Marzio A, Puccini J, Kwon Y, Maverakis NK, Arbini A, Sung P, Bar-Sagi D, Pagano M. Marzio A, et al. Mol Cell. 2019 Jan 17;73(2):224-237.e6. doi: 10.1016/j.molcel.2018.11.003. Epub 2018 Dec 13. Mol Cell. 2019. PMID: 30554948 Free PMC article.

5

Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs.

Clijsters L, Hoencamp C, Calis JJA, Marzio A, Handgraaf SM, Cuitino MC, Rosenberg BR, Leone G, Pagano M. Clijsters L, et al. Among authors: marzio a. Mol Cell. 2019 Jun 20;74(6):1264-1277.e7. doi: 10.1016/j.molcel.2019.04.010. Epub 2019 May 23. Mol Cell. 2019. PMID: 31130363 Free PMC article.

6

GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase.

Kuchay S, Wang H, Marzio A, Jain K, Homer H, Fehrenbacher N, Philips MR, Zheng N, Pagano M. Kuchay S, et al. Among authors: marzio a. Nat Struct Mol Biol. 2019 Jul;26(7):628-636. doi: 10.1038/s41594-019-0249-3. Epub 2019 Jun 17. Nat Struct Mol Biol. 2019. PMID: 31209342 Free PMC article.

7

PHOTACs enable optical control of protein degradation.

Reynders M, Matsuura BS, Bérouti M, Simoneschi D, Marzio A, Pagano M, Trauner D. Reynders M, et al. Among authors: marzio a. Sci Adv. 2020 Feb 21;6(8):eaay5064. doi: 10.1126/sciadv.aay5064. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128406 Free PMC article.

8

Loss of the deubiquitinase OTULIN promotes hepatocellular carcinoma (HCC) in an mTOR-dependent manner.

Marzio A, Pagano M. Marzio A, et al. Cell Death Differ. 2020 May;27(5):1455-1456. doi: 10.1038/s41418-020-0531-2. Epub 2020 Mar 30. Cell Death Differ. 2020. PMID: 32225171 Free PMC article. No abstract available.

9

TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response.

Young LM, Marzio A, Perez-Duran P, Reid DA, Meredith DN, Roberti D, Star A, Rothenberg E, Ueberheide B, Pagano M. Young LM, et al. Among authors: marzio a. Cell Rep. 2015 Oct 20;13(3):451-459. doi: 10.1016/j.celrep.2015.09.017. Epub 2015 Oct 8. Cell Rep. 2015. PMID: 26456830 Free PMC article.

10

EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion.

Marzio A, Kurz E, Sahni JM, Di Feo G, Puccini J, Jiang S, Hirsch CA, Arbini AA, Wu WL, Pass HI, Bar-Sagi D, Papagiannakopoulos T, Pagano M. Marzio A, et al. Cell. 2022 Jan 6;185(1):169-183.e19. doi: 10.1016/j.cell.2021.12.005. Epub 2021 Dec 27. Cell. 2022. PMID: 34963055 Free PMC article.

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