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Sortilin acts as an endocytic receptor for α-synuclein fibril.
Ishiyama S, Hasegawa T, Sugeno N, Kobayashi J, Yoshida S, Miki Y, Wakabayashi K, Fukuda M, Kawata Y, Nakamura T, Sato K, Ezura M, Kikuchi A, Takeda A, Aoki M. Ishiyama S, et al. Among authors: kobayashi j. FASEB J. 2023 Jul;37(7):e23017. doi: 10.1096/fj.202201605RR. FASEB J. 2023. PMID: 37272890
Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis.
Kobayashi J, Hasegawa T, Sugeno N, Yoshida S, Akiyama T, Fujimori K, Hatakeyama H, Miki Y, Tomiyama A, Kawata Y, Fukuda M, Kawahata I, Yamakuni T, Ezura M, Kikuchi A, Baba T, Takeda A, Kanzaki M, Wakabayashi K, Okano H, Aoki M. Kobayashi J, et al. FASEB J. 2019 Sep;33(9):10240-10256. doi: 10.1096/fj.201802051R. Epub 2019 Jun 18. FASEB J. 2019. PMID: 31211923
Altogether, these findings revealed a novel role of extracellular alpha-SYN on cellular trafficking of DAT and may provide a rationale for the cell type-specific, functional, and pathologic alterations in PD.-Kobayashi, J., Hasegawa, T., Sugeno, N., Yoshida, S., Aki …
Altogether, these findings revealed a novel role of extracellular alpha-SYN on cellular trafficking of DAT and may provide a rationale for t …
Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking.
Yoshida S, Hasegawa T, Suzuki M, Sugeno N, Kobayashi J, Ueyama M, Fukuda M, Ido-Fujibayashi A, Sekiguchi K, Ezura M, Kikuchi A, Baba T, Takeda A, Mochizuki H, Nagai Y, Aoki M. Yoshida S, et al. Among authors: kobayashi j. Hum Mol Genet. 2018 Mar 1;27(5):823-836. doi: 10.1093/hmg/ddy003. Hum Mol Genet. 2018. PMID: 29309590
DnaJ/Hsp40 Family and Parkinson's Disease.
Hasegawa T, Yoshida S, Sugeno N, Kobayashi J, Aoki M. Hasegawa T, et al. Among authors: kobayashi j. Front Neurosci. 2018 Jan 10;11:743. doi: 10.3389/fnins.2017.00743. eCollection 2017. Front Neurosci. 2018. PMID: 29367843 Free PMC article. Review.
ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways.
Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M, Tanaka N. Oshima R, et al. Among authors: kobayashi j. Sci Rep. 2016 Apr 26;6:24997. doi: 10.1038/srep24997. Sci Rep. 2016. PMID: 27112194 Free PMC article.
18F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies.
Ezura M, Kikuchi A, Okamura N, Ishiki A, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Yoshida S, Kobayashi J, Kobayashi M, Tano O, Ishiyama S, Nakamura T, Nakashima I, Mugikura S, Iwata R, Taki Y, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M. Ezura M, et al. Among authors: kobayashi j, kobayashi m. Front Aging Neurosci. 2021 Nov 29;13:761010. doi: 10.3389/fnagi.2021.761010. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34912209 Free PMC article.
Girdle Sensation Caused by Radiculitis due to Neurosarcoidosis.
Kobayashi J, Sugeno N, Shibui A, Aoki M. Kobayashi J, et al. Intern Med. 2015;54(12):1567-8. doi: 10.2169/internalmedicine.54.4242. Epub 2015 Jun 15. Intern Med. 2015. PMID: 26073252 Free article. No abstract available.
In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET.
Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Ezura M, Kobayashi M, Tano O, Mugikura S, Iwata R, Ishiki A, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M. Kikuchi A, et al. Among authors: kobayashi j, kobayashi m. Neurology. 2016 Nov 29;87(22):2309-2316. doi: 10.1212/WNL.0000000000003375. Epub 2016 Oct 28. Neurology. 2016. PMID: 27794115 Free PMC article.
2,062 results