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Mild SARS-CoV-2 infection results in long-lasting microbiota instability.
Upadhyay V, Suryawanshi RK, Tasoff P, McCavitt-Malvido M, Kumar RG, Murray VW, Noecker C, Bisanz JE, Hswen Y, Ha CWY, Sreekumar B, Chen IP, Lynch SV, Ott M, Lee S, Turnbaugh PJ. Upadhyay V, et al. Among authors: lee s. mBio. 2023 Aug 31;14(4):e0088923. doi: 10.1128/mbio.00889-23. Epub 2023 Jun 9. mBio. 2023. PMID: 37294090 Free PMC article.
A common allele of HLA mediates asymptomatic SARS-CoV-2 infection.
Augusto DG, Yusufali T, Sabatino JJ Jr, Peyser ND, Murdolo LD, Butcher X, Murray V, Pae V, Sarvadhavabhatla S, Beltran F, Gill G, Lynch K, Yun C, Maguire C, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Viera-Green CA, Spellman SR, Langton DJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Gras S, Maiers M, Hollenbach JA. Augusto DG, et al. Among authors: lee s. medRxiv [Preprint]. 2022 Oct 12:2021.05.13.21257065. doi: 10.1101/2021.05.13.21257065. medRxiv. 2022. PMID: 34031661 Free PMC article. Updated. Preprint.
A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.
Augusto DG, Murdolo LD, Chatzileontiadou DSM, Sabatino JJ Jr, Yusufali T, Peyser ND, Butcher X, Kizer K, Guthrie K, Murray VW, Pae V, Sarvadhavabhatla S, Beltran F, Gill GS, Lynch KL, Yun C, Maguire CT, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Vierra-Green CA, Spellman SR, Langton DJ, Dewar-Oldis MJ, Smith C, Barnard PJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Maiers M, Gras S, Hollenbach JA. Augusto DG, et al. Among authors: lee s. Nature. 2023 Aug;620(7972):128-136. doi: 10.1038/s41586-023-06331-x. Epub 2023 Jul 19. Nature. 2023. PMID: 37468623 Free PMC article.
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2.
Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young KC, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. Yin K, et al. Among authors: lee sa. Nat Immunol. 2024 Feb;25(2):218-225. doi: 10.1038/s41590-023-01724-6. Epub 2024 Jan 11. Nat Immunol. 2024. PMID: 38212464 Free PMC article.
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