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Thrombin-activated interleukin-1α drives atherogenesis, but also promotes vascular smooth muscle cell proliferation and collagen production.
Cardiovasc Res. 2023 Oct 16;119(12):2179-2189. doi: 10.1093/cvr/cvad091.
Cardiovasc Res. 2023.
PMID: 37309666
Free PMC article.
Alternative Pathways of IL-1 Activation, and Its Role in Health and Disease.
Pyrillou K, Burzynski LC, Clarke MCH.
Pyrillou K, et al. Among authors: burzynski lc.
Front Immunol. 2020 Dec 18;11:613170. doi: 10.3389/fimmu.2020.613170. eCollection 2020.
Front Immunol. 2020.
PMID: 33391283
Free PMC article.
Review.
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Platelet Isolation and Activation Assays.
Burzynski LC, Pugh N, Clarke MCH.
Burzynski LC, et al.
Bio Protoc. 2019 Oct 20;9(20):e3405. doi: 10.21769/BioProtoc.3405. eCollection 2019 Oct 20.
Bio Protoc. 2019.
PMID: 33654906
Free PMC article.
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Death Is Coming and the Clot Thickens, as Pyroptosis Feeds the Fire.
Burzynski LC, Clarke MCH.
Burzynski LC, et al.
Immunity. 2019 Jun 18;50(6):1339-1341. doi: 10.1016/j.immuni.2019.05.015.
Immunity. 2019.
PMID: 31216455
Free article.
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The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin.
Burzynski LC, Humphry M, Pyrillou K, Wiggins KA, Chan JNE, Figg N, Kitt LL, Summers C, Tatham KC, Martin PB, Bennett MR, Clarke MCH.
Burzynski LC, et al.
Immunity. 2019 Apr 16;50(4):1033-1042.e6. doi: 10.1016/j.immuni.2019.03.003. Epub 2019 Mar 26.
Immunity. 2019.
PMID: 30926232
Free PMC article.
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Interleukin-1α Activity in Necrotic Endothelial Cells Is Controlled by Caspase-1 Cleavage of Interleukin-1 Receptor-2: IMPLICATIONS FOR ALLOGRAFT REJECTION.
Burzynski LC, Humphry M, Bennett MR, Clarke MC.
Burzynski LC, et al.
J Biol Chem. 2015 Oct 9;290(41):25188-96. doi: 10.1074/jbc.M115.667915. Epub 2015 Aug 31.
J Biol Chem. 2015.
PMID: 26324711
Free PMC article.
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