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Page 1
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α.
Mawambo G, Oubaha M, Ichiyama Y, Blot G, Crespo-Garcia S, Dejda A, Binet F, Diaz-Marin R, Sawchyn C, Sergeev M, Juneau R, Kaufman RJ, Affar EB, Mallette FA, Wilson AM, Sapieha P. Mawambo G, et al. Among authors: mallette fa. J Neuroinflammation. 2023 Jun 21;20(1):145. doi: 10.1186/s12974-023-02793-y. J Neuroinflammation. 2023. PMID: 37344842 Free PMC article.
Targeting LINC00673 expression triggers cellular senescence in lung cancer.
Roth A, Boulay K, Groß M, Polycarpou-Schwarz M, Mallette FA, Regnier M, Bida O, Ginsberg D, Warth A, Schnabel PA, Muley T, Meister M, Zabeck H, Hoffmann H, Diederichs S. Roth A, et al. Among authors: mallette fa. RNA Biol. 2018;15(12):1499-1511. doi: 10.1080/15476286.2018.1553481. Epub 2018 Dec 7. RNA Biol. 2018. PMID: 30499379 Free PMC article.
Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.
Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, Silvis MR, Qutob N, van Rooijen E, Werner-Klein M, Li L, Dhawan D, Meierjohann S, Reimann M, Elkahloun A, Treitschke S, Dörken B, Speck C, Mallette FA, Zon LI, Holmen SL, Peeper DS, Samuels Y, Schmitt CA, Lee S. Yu Y, et al. Among authors: mallette fa. Cancer Cell. 2018 Apr 9;33(4):785. doi: 10.1016/j.ccell.2018.03.009. Cancer Cell. 2018. PMID: 29634951 Free article. No abstract available.
NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy.
Miloudi K, Oubaha M, Ménard C, Dejda A, Guber V, Cagnone G, Wilson AM, Tétreault N, Mawambo G, Binet F, Chidiac R, Delisle C, Buscarlet M, Cerani A, Crespo-Garcia S, Bentley K, Rezende F, Joyal JS, Mallette FA, Gratton JP, Larrivée B, Sapieha P. Miloudi K, et al. Among authors: mallette fa. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4538-4547. doi: 10.1073/pnas.1814711116. Epub 2019 Feb 20. Proc Natl Acad Sci U S A. 2019. PMID: 30787185 Free PMC article.
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy.
Binet F, Cagnone G, Crespo-Garcia S, Hata M, Neault M, Dejda A, Wilson AM, Buscarlet M, Mawambo GT, Howard JP, Diaz-Marin R, Parinot C, Guber V, Pilon F, Juneau R, Laflamme R, Sawchyn C, Boulay K, Leclerc S, Abu-Thuraia A, Côté JF, Andelfinger G, Rezende FA, Sennlaub F, Joyal JS, Mallette FA, Sapieha P. Binet F, et al. Among authors: mallette fa. Science. 2020 Aug 21;369(6506):eaay5356. doi: 10.1126/science.aay5356. Science. 2020. PMID: 32820093
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.
Crespo-Garcia S, Tsuruda PR, Dejda A, Ryan RD, Fournier F, Chaney SY, Pilon F, Dogan T, Cagnone G, Patel P, Buscarlet M, Dasgupta S, Girouard G, Rao SR, Wilson AM, O'Brien R, Juneau R, Guber V, Dubrac A, Beausejour C, Armstrong S, Mallette FA, Yohn CB, Joyal JS, Marquess D, Beltran PJ, Sapieha P. Crespo-Garcia S, et al. Among authors: mallette fa. Cell Metab. 2021 Apr 6;33(4):818-832.e7. doi: 10.1016/j.cmet.2021.01.011. Epub 2021 Feb 5. Cell Metab. 2021. PMID: 33548171 Free article.
53 results