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MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs' patients.
Catalano G, Zaza A, Banella C, Pelosi E, Castelli G, de Marinis E, Smigliani A, Travaglini S, Ottone T, Divona M, Del Principe MI, Buccisano F, Maurillo L, Ammatuna E, Testa U, Nervi C, Venditti A, Voso MT, Noguera NI. Catalano G, et al. Among authors: noguera ni. Leukemia. 2023 Aug;37(8):1600-1610. doi: 10.1038/s41375-023-01946-5. Epub 2023 Jun 22. Leukemia. 2023. PMID: 37349598
Identification of a potential "hotspot" DNA region in the RUNX1 gene targeted by mitoxantrone in therapy-related acute myeloid leukemia with t(16;21) translocation.
Ottone T, Hasan SK, Montefusco E, Curzi P, Mays AN, Chessa L, Ferrari A, Conte E, Noguera NI, Lavorgna S, Ammatuna E, Divona M, Bovetti K, Amadori S, Grimwade D, Lo-Coco F. Ottone T, et al. Among authors: noguera ni. Genes Chromosomes Cancer. 2009 Mar;48(3):213-21. doi: 10.1002/gcc.20633. Genes Chromosomes Cancer. 2009. PMID: 19023877
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