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Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers Derived from Plant Phenolic Acids.
Pharmaceutics. 2023 May 23;15(6):1572. doi: 10.3390/pharmaceutics15061572.
Pharmaceutics. 2023.
PMID: 37376020
Free PMC article.
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA.
Zhang D, Atochina-Vasserman EN, Maurya DS, Huang N, Xiao Q, Ona N, Liu M, Shahnawaz H, Ni H, Kim K, Billingsley MM, Pochan DJ, Mitchell MJ, Weissman D, Percec V.
Zhang D, et al.
J Am Chem Soc. 2021 Aug 11;143(31):12315-12327. doi: 10.1021/jacs.1c05813. Epub 2021 Jul 29.
J Am Chem Soc. 2021.
PMID: 34324336
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Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers.
Zhang D, Atochina-Vasserman EN, Maurya DS, Liu M, Xiao Q, Lu J, Lauri G, Ona N, Reagan EK, Ni H, Weissman D, Percec V.
Zhang D, et al.
J Am Chem Soc. 2021 Nov 3;143(43):17975-17982. doi: 10.1021/jacs.1c09585. Epub 2021 Oct 21.
J Am Chem Soc. 2021.
PMID: 34672554
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The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity.
Zhang D, Atochina-Vasserman EN, Lu J, Maurya DS, Xiao Q, Liu M, Adamson J, Ona N, Reagan EK, Ni H, Weissman D, Percec V.
Zhang D, et al.
J Am Chem Soc. 2022 Mar 23;144(11):4746-4753. doi: 10.1021/jacs.2c00273. Epub 2022 Mar 9.
J Am Chem Soc. 2022.
PMID: 35263098
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Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers.
Lu J, Atochina-Vasserman EN, Maurya DS, Sahoo D, Ona N, Reagan EK, Ni H, Weissman D, Percec V.
Lu J, et al.
J Am Chem Soc. 2023 Aug 30;145(34):18760-18766. doi: 10.1021/jacs.3c07337. Epub 2023 Aug 22.
J Am Chem Soc. 2023.
PMID: 37606244
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