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Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation.
Pfister SX, Markkanen E, Jiang Y, Sarkar S, Woodcock M, Orlando G, Mavrommati I, Pai CC, Zalmas LP, Drobnitzky N, Dianov GL, Verrill C, Macaulay VM, Ying S, La Thangue NB, D'Angiolella V, Ryan AJ, Humphrey TC. Pfister SX, et al. Among authors: humphrey tc. Cancer Cell. 2015 Nov 9;28(5):557-568. doi: 10.1016/j.ccell.2015.09.015. Cancer Cell. 2015. PMID: 26602815 Free PMC article.
DNA Double-Strand Break Repair Assay.
Pai CC, Blaikley E, Humphrey TC. Pai CC, et al. Among authors: humphrey tc. Cold Spring Harb Protoc. 2018 Apr 2;2018(4). doi: 10.1101/pdb.prot092031. Cold Spring Harb Protoc. 2018. PMID: 28733408
An essential role for dNTP homeostasis following CDK-induced replication stress.
Pai CC, Hsu KF, Durley SC, Keszthelyi A, Kearsey SE, Rallis C, Folkes LK, Deegan R, Wilkins SE, Pfister SX, De León N, Schofield CJ, Bähler J, Carr AM, Humphrey TC. Pai CC, et al. Among authors: humphrey tc. J Cell Sci. 2019 Mar 25;132(6):jcs226969. doi: 10.1242/jcs.226969. J Cell Sci. 2019. PMID: 30674555 Free PMC article.
44 results