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Mechano-dependent sorbitol accumulation supports biomolecular condensate.
Torrino S, Oldham WM, Tejedor AR, Burgos IS, Rachedi N, Fraissard K, Chauvet C, Sbai C, O'Hara BP, Abélanet S, Brau F, Clavel S, Collepardo-Guevara R, Espinosa JR, Ben-Sahra I, Bertero T. Torrino S, et al. Among authors: espinosa jr. bioRxiv [Preprint]. 2023 Jul 25:2023.07.24.550444. doi: 10.1101/2023.07.24.550444. bioRxiv. 2023. PMID: 37546967 Free PMC article. Preprint.
The liquid-to-solid transition of FUS is promoted by the condensate surface.
Shen Y, Chen A, Wang W, Shen Y, Ruggeri FS, Aime S, Wang Z, Qamar S, Espinosa JR, Garaizar A, St George-Hyslop P, Collepardo-Guevara R, Weitz DA, Vigolo D, Knowles TPJ. Shen Y, et al. Among authors: espinosa jr. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2301366120. doi: 10.1073/pnas.2301366120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549257 Free PMC article.
Location and Concentration of Aromatic-Rich Segments Dictates the Percolating Inter-Molecular Network and Viscoelastic Properties of Ageing Condensates.
Blazquez S, Sanchez-Burgos I, Ramirez J, Higginbotham T, Conde MM, Collepardo-Guevara R, Tejedor AR, Espinosa JR. Blazquez S, et al. Among authors: espinosa jr. Adv Sci (Weinh). 2023 Sep;10(25):e2207742. doi: 10.1002/advs.202207742. Epub 2023 Jun 29. Adv Sci (Weinh). 2023. PMID: 37386790 Free PMC article.
75 results