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An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress.
Igarashi T, Mazevet M, Yasuhara T, Yano K, Mochizuki A, Nishino M, Yoshida T, Yoshida Y, Takamatsu N, Yoshimi A, Shiraishi K, Horinouchi H, Kohno T, Hamamoto R, Adachi J, Zou L, Shiotani B. Igarashi T, et al. Among authors: shiotani b. Nat Commun. 2023 Aug 17;14(1):4991. doi: 10.1038/s41467-023-40578-2. Nat Commun. 2023. PMID: 37591859 Free PMC article.
Emerging strategies for cancer therapy by ATR inhibitors.
Yano K, Shiotani B. Yano K, et al. Among authors: shiotani b. Cancer Sci. 2023 Jul;114(7):2709-2721. doi: 10.1111/cas.15845. Epub 2023 May 15. Cancer Sci. 2023. PMID: 37189251 Free PMC article. Review.
ATR signaling at a glance.
Shiotani B, Zou L. Shiotani B, et al. J Cell Sci. 2009 Feb 1;122(Pt 3):301-4. doi: 10.1242/jcs.035105. J Cell Sci. 2009. PMID: 19158338 Free PMC article. No abstract available.
SMARCA4 deficiency-associated heterochromatin induces intrinsic DNA replication stress and susceptibility to ATR inhibition in lung adenocarcinoma.
Kurashima K, Kashiwagi H, Shimomura I, Suzuki A, Takeshita F, Mazevet M, Harata M, Yamashita T, Yamamoto Y, Kohno T, Shiotani B. Kurashima K, et al. Among authors: shiotani b. NAR Cancer. 2020 May 1;2(2):zcaa005. doi: 10.1093/narcan/zcaa005. eCollection 2020 Jun. NAR Cancer. 2020. PMID: 34316685 Free PMC article.
Chk1 and Claspin potentiate PCNA ubiquitination.
Yang XH, Shiotani B, Classon M, Zou L. Yang XH, et al. Among authors: shiotani b. Genes Dev. 2008 May 1;22(9):1147-52. doi: 10.1101/gad.1632808. Genes Dev. 2008. PMID: 18451105 Free PMC article.
30 results