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CRISPR screens decode cancer cell pathways that trigger γδ T cell detection.
Mamedov MR, Vedova S, Freimer JW, Sahu AD, Ramesh A, Arce MM, Meringa AD, Ota M, Chen PA, Hanspers K, Nguyen VQ, Takeshima KA, Rios AC, Pritchard JK, Kuball J, Sebestyen Z, Adams EJ, Marson A. Mamedov MR, et al. Among authors: kuball j. Nature. 2023 Sep;621(7977):188-195. doi: 10.1038/s41586-023-06482-x. Epub 2023 Aug 30. Nature. 2023. PMID: 37648854 Free PMC article.
γ9 and δ2CDR3 domains regulate functional avidity of T cells harboring γ9δ2TCRs.
Gründer C, van Dorp S, Hol S, Drent E, Straetemans T, Heijhuurs S, Scholten K, Scheper W, Sebestyen Z, Martens A, Strong R, Kuball J. Gründer C, et al. Among authors: kuball j. Blood. 2012 Dec 20;120(26):5153-62. doi: 10.1182/blood-2012-05-432427. Epub 2012 Sep 27. Blood. 2012. PMID: 23018643 Free article.
Cancer Immunotherapy Using γδT Cells: Dealing with Diversity.
Scheper W, Sebestyen Z, Kuball J. Scheper W, et al. Among authors: kuball j. Front Immunol. 2014 Nov 20;5:601. doi: 10.3389/fimmu.2014.00601. eCollection 2014. Front Immunol. 2014. PMID: 25477886 Free PMC article. Review.
RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor.
Sebestyen Z, Scheper W, Vyborova A, Gu S, Rychnavska Z, Schiffler M, Cleven A, Chéneau C, van Noorden M, Peigné CM, Olive D, Lebbink RJ, Oostvogels R, Mutis T, Schuurhuis GJ, Adams EJ, Scotet E, Kuball J. Sebestyen Z, et al. Among authors: kuball j. Cell Rep. 2016 May 31;15(9):1973-85. doi: 10.1016/j.celrep.2016.04.081. Epub 2016 May 19. Cell Rep. 2016. PMID: 27210746 Free PMC article.
Prevention of Vγ9Vδ2 T Cell Activation by a Vγ9Vδ2 TCR Nanobody.
de Bruin RC, Stam AG, Vangone A, van Bergen En Henegouwen PM, Verheul HM, Sebestyén Z, Kuball J, Bonvin AM, de Gruijl TD, van der Vliet HJ. de Bruin RC, et al. Among authors: kuball j. J Immunol. 2017 Jan 1;198(1):308-317. doi: 10.4049/jimmunol.1600948. Epub 2016 Nov 28. J Immunol. 2017. PMID: 27895170
Identification of a tumor-specific allo-HLA-restricted γδTCR.
Kierkels GJJ, Scheper W, Meringa AD, Johanna I, Beringer DX, Janssen A, Schiffler M, Aarts-Riemens T, Kramer L, Straetemans T, Heijhuurs S, Leusen JHW, San José E, Fuchs K, Griffioen M, Falkenburg JH, Bongiovanni L, de Bruin A, Vargas-Diaz D, Altelaar M, Heck AJR, Shultz LD, Ishikawa F, Nishimura MI, Sebestyén Z, Kuball J. Kierkels GJJ, et al. Among authors: kuball j. Blood Adv. 2019 Oct 8;3(19):2870-2882. doi: 10.1182/bloodadvances.2019032409. Blood Adv. 2019. PMID: 31585951 Free PMC article.
214 results