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A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations.
Ou J, Lewandowski EM, Hu Y, Lipinski AA, Aljasser A, Colon-Ascanio M, Morgan RT, Jacobs LMC, Zhang X, Bikowitz MJ, Langlais PR, Tan H, Wang J, Chen Y, Choy JS. Ou J, et al. Among authors: lewandowski em. PLoS Pathog. 2023 Aug 31;19(8):e1011592. doi: 10.1371/journal.ppat.1011592. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37651467 Free PMC article.
Low barrier hydrogen bonds in protein structure and function.
Kemp MT, Lewandowski EM, Chen Y. Kemp MT, et al. Among authors: lewandowski em. Biochim Biophys Acta Proteins Proteom. 2021 Jan;1869(1):140557. doi: 10.1016/j.bbapap.2020.140557. Epub 2020 Oct 23. Biochim Biophys Acta Proteins Proteom. 2021. PMID: 33148530 Free PMC article. Review.
Structural Insights into Molecular Recognition by Human Chemokine CCL19.
Lewandowski EM, Kroeck KG, Jacobs LMC, Fenske TG, Witt RN, Hintz AM, Ramsden ER, Zhang X, Peterson F, Volkman BF, Veldkamp CT, Chen Y. Lewandowski EM, et al. Biochemistry. 2022 Mar 1;61(5):311-318. doi: 10.1021/acs.biochem.1c00759. Epub 2022 Feb 14. Biochemistry. 2022. PMID: 35156805 Free PMC article.
A unique class of Zn2+-binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile.
Sacco MD, Wang S, Adapa SR, Zhang X, Lewandowski EM, Gongora MV, Keramisanou D, Atlas ZD, Townsend JA, Gatdula JR, Morgan RT, Hammond LR, Marty MT, Wang J, Eswara PJ, Gelis I, Jiang RHY, Sun X, Chen Y. Sacco MD, et al. Among authors: lewandowski em. Nat Commun. 2022 Jul 28;13(1):4370. doi: 10.1038/s41467-022-32086-6. Nat Commun. 2022. PMID: 35902581 Free PMC article.
20 results