Josephs TM - Search Results

1

A STAT3 protein complex required for mitochondrial mRNA stability and cancer.

Fernando CD, Jayasekara WSN, Inampudi C, Kohonen-Corish MRJ, Cooper WA, Beilharz TH, Josephs TM, Garama DJ, Gough DJ. Fernando CD, et al. Among authors: josephs tm. Cell Rep. 2023 Sep 26;42(9):113033. doi: 10.1016/j.celrep.2023.113033. Epub 2023 Sep 12. Cell Rep. 2023. PMID: 37703176 Free article.

2

Molecular challenges imposed by MHC-I restricted long epitopes on T cell immunity.

Josephs TM, Grant EJ, Gras S. Josephs TM, et al. Biol Chem. 2017 Aug 28;398(9):1027-1036. doi: 10.1515/hsz-2016-0305. Biol Chem. 2017. PMID: 28141543 Review.

3

Conformational change and human cytochrome c function: mutation of residue 41 modulates caspase activation and destabilizes Met-80 coordination.

Josephs TM, Liptak MD, Hughes G, Lo A, Smith RM, Wilbanks SM, Bren KL, Ledgerwood EC. Josephs TM, et al. J Biol Inorg Chem. 2013 Mar;18(3):289-97. doi: 10.1007/s00775-012-0973-1. Epub 2013 Jan 19. J Biol Inorg Chem. 2013. PMID: 23334161 Free PMC article.

4

Fasting-induced adipose factor identified as a key adipokine that is up-regulated in white adipose tissue during pregnancy and lactation in the rat.

Josephs T, Waugh H, Kokay I, Grattan D, Thompson M. Josephs T, et al. J Endocrinol. 2007 Aug;194(2):305-12. doi: 10.1677/JOE-07-0158. J Endocrinol. 2007. PMID: 17641280

5

Structure and dynamics of the CGRP receptor in apo and peptide-bound forms.

Josephs TM, Belousoff MJ, Liang YL, Piper SJ, Cao J, Garama DJ, Leach K, Gregory KJ, Christopoulos A, Hay DL, Danev R, Wootten D, Sexton PM. Josephs TM, et al. Science. 2021 Apr 9;372(6538):eabf7258. doi: 10.1126/science.abf7258. Epub 2021 Feb 18. Science. 2021. PMID: 33602864

6

Epitope length variants balance protective immune responses and viral escape in HIV-1 infection.

Pymm P, Tenzer S, Wee E, Weimershaus M, Burgevin A, Kollnberger S, Gerstoft J, Josephs TM, Ladell K, McLaren JE, Appay V, Price DA, Fugger L, Bell JI, Schild H, van Endert P, Harkiolaki M, Iversen AKN. Pymm P, et al. Among authors: josephs tm. Cell Rep. 2022 Mar 1;38(9):110449. doi: 10.1016/j.celrep.2022.110449. Cell Rep. 2022. PMID: 35235807 Free PMC article.

7

Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3.

Russell IC, Zhang X, Bumbak F, McNeill SM, Josephs TM, Leeming MG, Christopoulos G, Venugopal H, Flocco MM, Sexton PM, Wootten D, Belousoff MJ. Russell IC, et al. Among authors: josephs tm. Biochemistry. 2024 Mar 5;63(5):625-631. doi: 10.1021/acs.biochem.3c00647. Epub 2024 Feb 20. Biochemistry. 2024. PMID: 38376112

8

Personalised medicines for familial hypercalcemia and hyperparathyroidism.

Josephs TM, Zhang F, Dinh LV, Keller AN, Conigrave AD, Capuano B, Gregory KJ, Leach K. Josephs TM, et al. J Mol Endocrinol. 2022 May 9;69(1):243-257. doi: 10.1530/JME-21-0263. J Mol Endocrinol. 2022. PMID: 35318962

9

Therapeutic Opportunities of Targeting Allosteric Binding Sites on the Calcium-Sensing Receptor.

Diao J, DeBono A, Josephs TM, Bourke JE, Capuano B, Gregory KJ, Leach K. Diao J, et al. Among authors: josephs tm. ACS Pharmacol Transl Sci. 2021 Mar 8;4(2):666-679. doi: 10.1021/acsptsci.1c00046. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2021. PMID: 33860192 Free PMC article. Review.

10

Development of AC265347-Inspired Calcium-Sensing Receptor Ago-Positive Allosteric Modulators.

Dinh LV, DeBono A, Keller AN, Josephs TM, Gregory KJ, Leach K, Capuano B. Dinh LV, et al. Among authors: josephs tm. ChemMedChem. 2021 Nov 19;16(22):3451-3462. doi: 10.1002/cmdc.202100368. Epub 2021 Jul 29. ChemMedChem. 2021. PMID: 34216111

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