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Muscle dysfunction in a zebrafish model of Duchenne muscular dystrophy.
Widrick JJ, Alexander MS, Sanchez B, Gibbs DE, Kawahara G, Beggs AH, Kunkel LM. Widrick JJ, et al. Physiol Genomics. 2016 Nov 1;48(11):850-860. doi: 10.1152/physiolgenomics.00088.2016. Epub 2016 Oct 7. Physiol Genomics. 2016. PMID: 27764767 Free PMC article.
The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice.
Hightower RM, Reid AL, Gibbs DE, Wang Y, Widrick JJ, Kunkel LM, Kastenschmidt JM, Villalta SA, van Groen T, Chang H, Gornisiewicz S, Landesman Y, Tamir S, Alexander MS. Hightower RM, et al. Among authors: widrick jj. Mol Ther. 2020 Jan 8;28(1):189-201. doi: 10.1016/j.ymthe.2019.08.016. Epub 2019 Sep 3. Mol Ther. 2020. PMID: 31628052 Free PMC article.
miR-486 is essential for muscle function and suppresses a dystrophic transcriptome.
Samani A, Hightower RM, Reid AL, English KG, Lopez MA, Doyle JS, Conklin MJ, Schneider DA, Bamman MM, Widrick JJ, Crossman DK, Xie M, Jee D, Lai EC, Alexander MS. Samani A, et al. Among authors: widrick jj. Life Sci Alliance. 2022 May 5;5(9):e202101215. doi: 10.26508/lsa.202101215. Print 2022 Sep. Life Sci Alliance. 2022. PMID: 35512829 Free PMC article.
Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling.
Kawahara G, Gasperini MJ, Myers JA, Widrick JJ, Eran A, Serafini PR, Alexander MS, Pletcher MT, Morris CA, Kunkel LM. Kawahara G, et al. Among authors: widrick jj. Hum Mol Genet. 2014 Apr 1;23(7):1869-78. doi: 10.1093/hmg/ddt579. Epub 2013 Nov 13. Hum Mol Genet. 2014. PMID: 24234649 Free PMC article.
A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies.
Serafini PR, Feyder MJ, Hightower RM, Garcia-Perez D, Vieira NM, Lek A, Gibbs DE, Moukha-Chafiq O, Augelli-Szafran CE, Kawahara G, Widrick JJ, Kunkel LM, Alexander MS. Serafini PR, et al. Among authors: widrick jj. JCI Insight. 2018 Sep 20;3(18):e120493. doi: 10.1172/jci.insight.120493. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232282 Free PMC article.
MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.
Alexander MS, Casar JC, Motohashi N, Vieira NM, Eisenberg I, Marshall JL, Gasperini MJ, Lek A, Myers JA, Estrella EA, Kang PB, Shapiro F, Rahimov F, Kawahara G, Widrick JJ, Kunkel LM. Alexander MS, et al. Among authors: widrick jj. J Clin Invest. 2014 Jun;124(6):2651-67. doi: 10.1172/JCI73579. Epub 2014 May 1. J Clin Invest. 2014. PMID: 24789910 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35560247
Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling.
Kawahara G, Gasperini MJ, Myers JA, Widrick JJ, Eran A, Serafini PR, Alexander MS, Pletcher MT, Morris CA, Kunkel LM. Kawahara G, et al. Among authors: widrick jj. Hum Mol Genet. 2015 Aug 1;24(15):4480-1. doi: 10.1093/hmg/ddv169. Epub 2015 Jun 1. Hum Mol Genet. 2015. PMID: 26034133 Free PMC article. No abstract available.
84 results