Horton JD - Search Results

1

Regulated adipose tissue-specific expression of human AGPAT2 in lipodystrophic Agpat2-null mice results in regeneration of adipose tissue.

Agarwal AK, Tunison K, Vale G, McDonald JG, Li X, Scherer PE, Horton JD, Garg A. Agarwal AK, et al. Among authors: horton jd. iScience. 2023 Sep 1;26(10):107806. doi: 10.1016/j.isci.2023.107806. eCollection 2023 Oct 20. iScience. 2023. PMID: 37752957 Free PMC article.

2

Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy.

Cortés VA, Curtis DE, Sukumaran S, Shao X, Parameswara V, Rashid S, Smith AR, Ren J, Esser V, Hammer RE, Agarwal AK, Horton JD, Garg A. Cortés VA, et al. Among authors: horton jd. Cell Metab. 2009 Feb;9(2):165-76. doi: 10.1016/j.cmet.2009.01.002. Cell Metab. 2009. PMID: 19187773 Free PMC article.

3

Human 1-acylglycerol-3-phosphate O-acyltransferase isoforms 1 and 2: biochemical characterization and inability to rescue hepatic steatosis in Agpat2(-/-) gene lipodystrophic mice.

Agarwal AK, Sukumaran S, Cortés VA, Tunison K, Mizrachi D, Sankella S, Gerard RD, Horton JD, Garg A. Agarwal AK, et al. Among authors: horton jd. J Biol Chem. 2011 Oct 28;286(43):37676-91. doi: 10.1074/jbc.M111.250449. Epub 2011 Aug 27. J Biol Chem. 2011. PMID: 21873652 Free PMC article.

4

Enhanced fatty acid flux triggered by adiponectin overexpression.

Shetty S, Ramos-Roman MA, Cho YR, Brown J, Plutzky J, Muise ES, Horton JD, Scherer PE, Parks EJ. Shetty S, et al. Among authors: horton jd. Endocrinology. 2012 Jan;153(1):113-22. doi: 10.1210/en.2011-1339. Epub 2011 Nov 1. Endocrinology. 2012. PMID: 22045665 Free PMC article.

5

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism.

Deng Y, Wang ZV, Tao C, Gao N, Holland WL, Ferdous A, Repa JJ, Liang G, Ye J, Lehrman MA, Hill JA, Horton JD, Scherer PE. Deng Y, et al. Among authors: horton jd. J Clin Invest. 2013 Jan;123(1):455-68. doi: 10.1172/JCI62819. Epub 2012 Dec 21. J Clin Invest. 2013. PMID: 23257357 Free PMC article.

6

Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors.

Cortés VA, Cautivo KM, Rong S, Garg A, Horton JD, Agarwal AK. Cortés VA, et al. Among authors: horton jd. J Lipid Res. 2014 Feb;55(2):276-88. doi: 10.1194/jlr.M045799. Epub 2013 Nov 30. J Lipid Res. 2014. PMID: 24293639 Free PMC article.

7

Hepatic gluconeogenesis is enhanced by phosphatidic acid which remains uninhibited by insulin in lipodystrophic Agpat2-/- mice.

Sankella S, Garg A, Horton JD, Agarwal AK. Sankella S, et al. Among authors: horton jd. J Biol Chem. 2014 Feb 21;289(8):4762-77. doi: 10.1074/jbc.M113.530998. Epub 2014 Jan 14. J Biol Chem. 2014. PMID: 24425876 Free PMC article.

8

Mogat1 deletion does not ameliorate hepatic steatosis in lipodystrophic (Agpat2-/-) or obese (ob/ob) mice.

Agarwal AK, Tunison K, Dalal JS, Yen CL, Farese RV Jr, Horton JD, Garg A. Agarwal AK, et al. Among authors: horton jd. J Lipid Res. 2016 Apr;57(4):616-30. doi: 10.1194/jlr.M065896. Epub 2016 Feb 15. J Lipid Res. 2016. PMID: 26880786 Free PMC article.

9

AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue.

Cautivo KM, Lizama CO, Tapia PJ, Agarwal AK, Garg A, Horton JD, Cortés VA. Cautivo KM, et al. Among authors: horton jd. Mol Metab. 2016 May 13;5(7):491-505. doi: 10.1016/j.molmet.2016.05.004. eCollection 2016 Jul. Mol Metab. 2016. PMID: 27408775 Free PMC article.

10

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice.

Rong S, Cortés VA, Rashid S, Anderson NN, McDonald JG, Liang G, Moon YA, Hammer RE, Horton JD. Rong S, et al. Among authors: horton jd. Elife. 2017 Feb 28;6:e25015. doi: 10.7554/eLife.25015. Elife. 2017. PMID: 28244871 Free PMC article.

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