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Page 1
Unlocking bacterial defense: Exploring the potent inhibition of NorA efflux pump by coumarin derivatives in Staphylococcus aureus.
Martin ALAR, Pereira RLS, Rocha JE, Farias PAM, Freitas TS, Caldas FRL, Figueredo FG, Sampaio NFL, Oliveira-Tintino CDM, Tintino SR, da Hora GCA, Lima MCP, de Menezes IRA, Carvalho DT, Coutinho HDM, Fonteles MMF. Martin ALAR, et al. Among authors: freitas ts. Microb Pathog. 2024 May;190:106608. doi: 10.1016/j.micpath.2024.106608. Epub 2024 Mar 20. Microb Pathog. 2024. PMID: 38503396
In vitro evaluation of the susceptibility of bacterial biofilms to hecogenin acetate.
Araújo NJS, Costa MDS, da Silva ARP, Paulo CLR, Silva CAP, Felix FJ, Oliveira-Tintino CDM, Filho JMB, de Freitas TS, Braga MFBM, Coutinho HDM, Andrade-Pinheiro JC. Araújo NJS, et al. Among authors: de freitas ts. Acta Trop. 2024 May;253:107157. doi: 10.1016/j.actatropica.2024.107157. Epub 2024 Feb 22. Acta Trop. 2024. PMID: 38387772
Evaluation of the antibacterial and inhibitory activity of the MepA efflux pump of Staphylococcus aureus by riparins I, II, III, and IV.
Rodrigues Dos Santos Barbosa C, Macêdo NS, de Sousa Silveira Z, Rocha JE, Freitas TS, Muniz DF, Araújo IM, Datiane de Morais Oliveira-Tintino C, Marinho ES, Nunes da Rocha M, Marinho MM, Bezerra AH, Ribeiro de Sousa G, Barbosa-Filho JM, de Souza-Ferrari J, Melo Coutinho HD, Silva Dos Santos H, Bezerra da Cunha FA. Rodrigues Dos Santos Barbosa C, et al. Among authors: freitas ts. Arch Biochem Biophys. 2023 Oct 15;748:109782. doi: 10.1016/j.abb.2023.109782. Epub 2023 Oct 13. Arch Biochem Biophys. 2023. PMID: 37839789
Synthesis, spectroscopic characterization, and antibacterial activity of chalcone (2E)-1-(3'-aminophenyl)-3-(4-dimethylaminophenyl)-prop-2-en-1-one against multiresistant Staphylococcus aureus carrier of efflux pump mechanisms and β-lactamase.
da Silva L, Donato IA, Bezerra SR, Dos Santos HS, Bandeira PN, do Nascimento MTR, Guedes JM, Freitas PR, de Araújo ACJ, de Freitas TS, Coutinho HDM, de Matos YMLS, de Oliveira LCC, da Cunha FAB. da Silva L, et al. Among authors: de freitas ts. Fundam Clin Pharmacol. 2024 Feb;38(1):60-71. doi: 10.1111/fcp.12938. Epub 2023 Jul 27. Fundam Clin Pharmacol. 2024. PMID: 37497790
In vitro and in silico evidences about the inhibition of MepA efflux pump by coumarin derivatives.
Martin ALAR, Pereira RLS, Rocha JE, Farias PAM, Freitas TS, de Lemos Caldas FR, Figueredo FG, Sampaio NFL, Ribeiro-Filho J, Menezes IRA, Brancaglion GA, de Paulo DC, Carvalho DT, Lima MA, Coutinho HDM, Fonteles MMF. Martin ALAR, et al. Among authors: freitas ts. Microb Pathog. 2023 Sep;182:106246. doi: 10.1016/j.micpath.2023.106246. Epub 2023 Jul 14. Microb Pathog. 2023. PMID: 37454945
Synthesis, structural, characterization, antibacterial and antibiotic modifying activity, ADMET study, molecular docking and dynamics of chalcone (E)-1-(4-aminophenyl)-3-(4-nitrophenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps.
Souza MA, Rodrigues LG, Rocha JE, de Freitas TS, Bandeira PN, Marinho MM, Nunes da Rocha M, Marinho ES, Honorato Barreto AC, Coutinho HDM, Silva LMA, Julião MSDS, Marques Canuto K, Marques da Fonseca A, Teixeira AMR, Dos Santos HS. Souza MA, et al. Among authors: de freitas ts. J Biomol Struct Dyn. 2024 Feb-Mar;42(4):1670-1691. doi: 10.1080/07391102.2023.2213777. Epub 2023 May 24. J Biomol Struct Dyn. 2024. PMID: 37222682
In vitro and in silico antibacterial evaluation of coumarin derivatives against MDR strains of Staphylococcus aureus and Escherichia coli.
Martin ALAR, De Menezes IRA, Sousa AK, Farias PAM, Dos Santos FAV, Freitas TS, Figueredo FG, Ribeiro-Filho J, Carvalho DT, Coutinho HDM, Fonteles MMF. Martin ALAR, et al. Among authors: freitas ts. Microb Pathog. 2023 Apr;177:106058. doi: 10.1016/j.micpath.2023.106058. Epub 2023 Mar 5. Microb Pathog. 2023. PMID: 36878333
LC-MS Analysis and Antifungal Activity of Turnera subulata Sm.
Andrade-Pinheiro JC, Sobral de Souza CE, Ribeiro DA, Silva AA, da Silva VB, Dos Santos ATL, Juno Alencar Fonseca V, de Macêdo DG, da Cruz RP, Almeida-Bezerra JW, Machado AJT, de Freitas TS, de Brito ES, Ribeiro PRV, da Costa JGM, Coutinho HDM, Kowalska G, Rowiński R, Kowalski R, Morais-Braga MFB. Andrade-Pinheiro JC, et al. Among authors: de freitas ts. Plants (Basel). 2023 Jan 16;12(2):415. doi: 10.3390/plants12020415. Plants (Basel). 2023. PMID: 36679128 Free PMC article.
Potentiation of Antibiotic Action and Efflux Pump Inhibitory Effect on Staphylococcus aureus Strains by Solasodine.
da Silva ARP, Costa MDS, Araújo NJS, de Freitas TS, de Almeida RS, Barbosa Filho JM, Tavares JF, de Souza EO, de Farias PAM, Pinheiro JCA, Coutinho HDM. da Silva ARP, et al. Among authors: de freitas ts. Antibiotics (Basel). 2022 Sep 27;11(10):1309. doi: 10.3390/antibiotics11101309. Antibiotics (Basel). 2022. PMID: 36289967 Free PMC article.
Dihydroeugenol derivatives associated with blue LED light: A different form to face multidrug resistant (MDR) bacteria.
de Sousa AK, Rocha JE, de Freitas TS, Freitas PR, Pereira RLS, Leandro MKDNS, Machado JVC, de Oliveira LM, Torres Sierra EJ, Pereira Júnior FN, Carvalho DT, Coutinho HDM, Quintans Júnior LJ. de Sousa AK, et al. Among authors: de freitas ts. Microb Pathog. 2022 Dec;173(Pt A):105827. doi: 10.1016/j.micpath.2022.105827. Epub 2022 Oct 13. Microb Pathog. 2022. PMID: 36243385
57 results