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Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation.
J Med Chem. 2023 Nov 23;66(22):15171-15188. doi: 10.1021/acs.jmedchem.3c01095. Epub 2023 Oct 17.
J Med Chem. 2023.
PMID: 37847303
Identification of ortho-hydroxy anilide as a novel scaffold for lysine demethylase 5 inhibitors.
Jaikhan P, Buranrat B, Itoh Y, Chotitumnavee J, Kurohara T, Suzuki T.
Jaikhan P, et al.
Bioorg Med Chem Lett. 2019 May 15;29(10):1173-1176. doi: 10.1016/j.bmcl.2019.03.028. Epub 2019 Mar 21.
Bioorg Med Chem Lett. 2019.
PMID: 30928196
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Histone Deacetylases Enhance Ca2+-Activated K⁺ Channel KCa3.1 Expression in Murine Inflammatory CD4⁺ T Cells.
Matsui M, Terasawa K, Kajikuri J, Kito H, Endo K, Jaikhan P, Suzuki T, Ohya S.
Matsui M, et al. Among authors: jaikhan p.
Int J Mol Sci. 2018 Sep 27;19(10):2942. doi: 10.3390/ijms19102942.
Int J Mol Sci. 2018.
PMID: 30262728
Free PMC article.
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CRTC1 Nuclear Translocation Following Learning Modulates Memory Strength via Exchange of Chromatin Remodeling Complexes on the Fgf1 Gene.
Uchida S, Teubner BJW, Hevi C, Hara K, Kobayashi A, Dave RM, Shintaku T, Jaikhan P, Yamagata H, Suzuki T, Watanabe Y, Zakharenko SS, Shumyatsky GP.
Uchida S, et al. Among authors: jaikhan p.
Cell Rep. 2017 Jan 10;18(2):352-366. doi: 10.1016/j.celrep.2016.12.052.
Cell Rep. 2017.
PMID: 28076781
Free PMC article.
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Design and Synthesis of Nicotinic Acetylcholine Receptor Antagonists and their Effect on Cognitive Impairment.
Jaikhan P, Boonyarat C, Arunrungvichian K, Taylor P, Vajragupta O.
Jaikhan P, et al.
Chem Biol Drug Des. 2016 Jan;87(1):39-56. doi: 10.1111/cbdd.12627. Epub 2015 Aug 27.
Chem Biol Drug Des. 2016.
PMID: 26235313
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