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Identification of the regulatory circuit governing corneal epithelial fate determination and disease.
Smits JGA, Cunha DL, Amini M, Bertolin M, Laberthonnière C, Qu J, Owen N, Latta L, Seitz B, Roux LN, Stachon T, Ferrari S, Moosajee M, Aberdam D, Szentmary N, van Heeringen SJ, Zhou H. Smits JGA, et al. Among authors: van heeringen sj. PLoS Biol. 2023 Oct 19;21(10):e3002336. doi: 10.1371/journal.pbio.3002336. eCollection 2023 Oct. PLoS Biol. 2023. PMID: 37856539 Free PMC article.
p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.
Richardson R, Mitchell K, Hammond NL, Mollo MR, Kouwenhoven EN, Wyatt ND, Donaldson IJ, Zeef L, Burgis T, Blance R, van Heeringen SJ, Stunnenberg HG, Zhou H, Missero C, Romano RA, Sinha S, Dixon MJ, Dixon J. Richardson R, et al. Among authors: van heeringen sj. PLoS Genet. 2017 Jun 12;13(6):e1006828. doi: 10.1371/journal.pgen.1006828. eCollection 2017 Jun. PLoS Genet. 2017. PMID: 28604778 Free PMC article.
Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome.
Soares E, Xu Q, Li Q, Qu J, Zheng Y, Raeven HHM, Brandao KO, Petit I, van den Akker WMR, van Heeringen SJ, Aberdam D, Tang F, Zhou H. Soares E, et al. Among authors: van heeringen sj, van den akker wmr. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17361-17370. doi: 10.1073/pnas.1908180116. Epub 2019 Aug 14. Proc Natl Acad Sci U S A. 2019. PMID: 31413199 Free PMC article.
The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A.
Smits JPH, Qu J, Pardow F, van den Brink NJM, Rodijk-Olthuis D, van Vlijmen-Willems IMJJ, van Heeringen SJ, Zeeuwen PLJM, Schalkwijk J, Zhou H, van den Bogaard EH. Smits JPH, et al. Among authors: van heeringen sj. bioRxiv [Preprint]. 2023 Jun 8:2023.06.07.544032. doi: 10.1101/2023.06.07.544032. bioRxiv. 2023. PMID: 37333234 Free PMC article. Updated. Preprint.
Seq2science: an end-to-end workflow for functional genomics analysis.
van der Sande M, Frölich S, Schäfers T, Smits JGA, Snabel RR, Rinzema S, van Heeringen SJ. van der Sande M, et al. Among authors: van heeringen sj. PeerJ. 2023 Nov 15;11:e16380. doi: 10.7717/peerj.16380. eCollection 2023. PeerJ. 2023. PMID: 38025697 Free PMC article.
scANANSE gene regulatory network and motif analysis of single-cell clusters.
Smits JGA, Arts JA, Frölich S, Snabel RR, Heuts BMH, Martens JHA, van Heeringen SJ, Zhou H. Smits JGA, et al. Among authors: van heeringen sj. F1000Res. 2023 Mar 6;12:243. doi: 10.12688/f1000research.130530.1. eCollection 2023. F1000Res. 2023. PMID: 38116584 Free PMC article.
The Aryl Hydrocarbon Receptor Regulates Epidermal Differentiation through Transient Activation of TFAP2A.
Smits JPH, Qu J, Pardow F, van den Brink NJM, Rodijk-Olthuis D, van Vlijmen-Willems IMJJ, van Heeringen SJ, Zeeuwen PLJM, Schalkwijk J, Zhou H, van den Bogaard EH. Smits JPH, et al. Among authors: van heeringen sj. J Invest Dermatol. 2024 Feb 22:S0022-202X(24)00114-3. doi: 10.1016/j.jid.2024.01.030. Online ahead of print. J Invest Dermatol. 2024. PMID: 38401701
54 results