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Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease.
Matthews I, Birnbaum A, Gromova A, Huang AW, Liu K, Liu EA, Coutinho K, McGraw M, Patterson DC, Banks MT, Nobles AC, Nguyen N, Merrihew GE, Wang L, Baeuerle E, Fernandez E, Musi N, MacCoss MJ, Miranda HC, La Spada AR, Cortes CJ. Matthews I, et al. Among authors: huang aw. Cell Rep. 2023 Nov 28;42(11):113436. doi: 10.1016/j.celrep.2023.113436. Epub 2023 Nov 11. Cell Rep. 2023. PMID: 37952157 Free PMC article.
MOTS-c reduces myostatin and muscle atrophy signaling.
Kumagai H, Coelho AR, Wan J, Mehta HH, Yen K, Huang A, Zempo H, Fuku N, Maeda S, Oliveira PJ, Cohen P, Kim SJ. Kumagai H, et al. Am J Physiol Endocrinol Metab. 2021 Apr 1;320(4):E680-E690. doi: 10.1152/ajpendo.00275.2020. Epub 2021 Feb 8. Am J Physiol Endocrinol Metab. 2021. PMID: 33554779 Free PMC article.
A naturally occurring variant of SHLP2 is a protective factor in Parkinson's disease.
Kim SJ, Miller B, Hartel NG, Ramirez R 2nd, Braniff RG, Leelaprachakul N, Huang A, Wang Y, Arpawong TE, Crimmins EM, Wang P, Sun X, Liu C, Levy D, Yen K, Petzinger GM, Graham NA, Jakowec MW, Cohen P. Kim SJ, et al. Mol Psychiatry. 2024 Feb;29(2):505-517. doi: 10.1038/s41380-023-02344-0. Epub 2024 Jan 3. Mol Psychiatry. 2024. PMID: 38167865 Free PMC article.
Infections, Hospitalizations, and Deaths Among US Nursing Home Residents With vs Without a SARS-CoV-2 Vaccine Booster.
McConeghy KW, Bardenheier B, Huang AW, White EM, Feifer RA, Blackman C, Santostefano CM, Lee Y, DeVone F, Halladay CW, Rudolph JL, Zullo AR, Mor V, Gravenstein S. McConeghy KW, et al. Among authors: huang aw. JAMA Netw Open. 2022 Dec 1;5(12):e2245417. doi: 10.1001/jamanetworkopen.2022.45417. JAMA Netw Open. 2022. PMID: 36477482 Free PMC article.
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