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Fatty acid desaturation and lipoxygenase pathways support trained immunity.
Ferreira AV, Alarcon-Barrera JC, Domínguez-Andrés J, Bulut Ö, Kilic G, Debisarun PA, Röring RJ, Özhan HN, Terschlüsen E, Ziogas A, Kostidis S, Mohammed Y, Matzaraki V, Renieris G, Giamarellos-Bourboulis EJ, Netea MG, Giera M. Ferreira AV, et al. Nat Commun. 2023 Nov 15;14(1):7385. doi: 10.1038/s41467-023-43315-x. Nat Commun. 2023. PMID: 37968313 Free PMC article.
Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock.
Ferwerda B, Alonso S, Banahan K, McCall MB, Giamarellos-Bourboulis EJ, Ramakers BP, Mouktaroudi M, Fain PR, Izagirre N, Syafruddin D, Cristea T, Mockenhaupt FP, Troye-Blomberg M, Kumpf O, Maiga B, Dolo A, Doumbo O, Sundaresan S, Bedu-Addo G, van Crevel R, Hamann L, Oh DY, Schumann RR, Joosten LA, de la Rúa C, Sauerwein R, Drenth JP, Kullberg BJ, van der Ven AJ, Hill AV, Pickkers P, van der Meer JW, O'Neill LA, Netea MG. Ferwerda B, et al. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10272-7. doi: 10.1073/pnas.0811273106. Epub 2009 Jun 9. Proc Natl Acad Sci U S A. 2009. PMID: 19509334 Free PMC article.
Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis.
Joosten LA, Netea MG, Mylona E, Koenders MI, Malireddi RK, Oosting M, Stienstra R, van de Veerdonk FL, Stalenhoef AF, Giamarellos-Bourboulis EJ, Kanneganti TD, van der Meer JW. Joosten LA, et al. Arthritis Rheum. 2010 Nov;62(11):3237-48. doi: 10.1002/art.27667. Arthritis Rheum. 2010. PMID: 20662061 Free PMC article.
Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis caused by Gram-negative bacteria: results from a randomized clinical study.
Spyridaki A, Raftogiannis M, Antonopoulou A, Tsaganos T, Routsi C, Baziaka F, Karagianni V, Mouktaroudi M, Koutoukas P, Pelekanou A, Kotanidou A, Orfanos SE, van der Meer JW, Netea MG, Giamarellos-Bourboulis EJ. Spyridaki A, et al. Antimicrob Agents Chemother. 2012 Jul;56(7):3819-25. doi: 10.1128/AAC.05798-11. Epub 2012 May 7. Antimicrob Agents Chemother. 2012. PMID: 22564837 Free PMC article. Clinical Trial.
Deficient Candida-specific T-helper 17 response during sepsis.
van de Veerdonk FL, Mouktaroudi M, Ramakers BP, Pistiki A, Pickkers P, van der Meer JW, Netea MG, Giamarellos-Bourboulis EJ. van de Veerdonk FL, et al. J Infect Dis. 2012 Dec 1;206(11):1798-802. doi: 10.1093/infdis/jis596. Epub 2012 Sep 14. J Infect Dis. 2012. PMID: 22984119
501 results