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Immunopeptidome Analysis of HLA-DPB1 Allelic Variants Reveals New Functional Hierarchies.
van Balen P, Kester MGD, de Klerk W, Crivello P, Arrieta-Bolaños E, de Ru AH, Jedema I, Mohammed Y, Heemskerk MHM, Fleischhauer K, van Veelen PA, Falkenburg JHF. van Balen P, et al. Among authors: kester mgd. J Immunol. 2020 Jun 15;204(12):3273-3282. doi: 10.4049/jimmunol.2000192. Epub 2020 Apr 29. J Immunol. 2020. PMID: 32350084
Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity.
Laghmouchi A, Kester MGD, Hoogstraten C, Hageman L, de Klerk W, Huisman W, Koster EAS, de Ru AH, van Balen P, Klobuch S, van Veelen PA, Falkenburg JHF, Jedema I. Laghmouchi A, et al. Among authors: kester mgd. Front Immunol. 2022 Feb 16;13:831822. doi: 10.3389/fimmu.2022.831822. eCollection 2022. Front Immunol. 2022. PMID: 35251023 Free PMC article.
Human T cells recognize HLA-DP-bound peptides in two orientations.
Klobuch S, Lim JJ, van Balen P, Kester MGD, de Klerk W, de Ru AH, Pothast CR, Jedema I, Drijfhout JW, Rossjohn J, Reid HH, van Veelen PA, Falkenburg JHF, Heemskerk MHM. Klobuch S, et al. Among authors: kester mgd. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2214331119. doi: 10.1073/pnas.2214331119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442096 Free PMC article.
Expanding the repertoire reveals recurrent, cryptic, and hematopoietic HLA class I minor histocompatibility antigens.
Fuchs KJ, van de Meent M, Honders MW, Khatri I, Kester MGD, Koster EAS, Koutsoumpli G, de Ru AH, van Bergen CAM, van Veelen PA, 't Hoen PAC, van Balen P, van den Akker EB, Veelken JH, Halkes CJM, Falkenburg JHF, Griffioen M. Fuchs KJ, et al. Among authors: kester mgd. Blood. 2024 May 2;143(18):1856-1872. doi: 10.1182/blood.2023022343. Blood. 2024. PMID: 38427583 Free PMC article.
Allo-HLA reactivity of virus-specific memory T cells is common.
Amir AL, D'Orsogna LJ, Roelen DL, van Loenen MM, Hagedoorn RS, de Boer R, van der Hoorn MA, Kester MG, Doxiadis II, Falkenburg JH, Claas FH, Heemskerk MH. Amir AL, et al. Blood. 2010 Apr 15;115(15):3146-57. doi: 10.1182/blood-2009-07-234906. Epub 2010 Feb 16. Blood. 2010. PMID: 20160165 Free article.
95 results