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α-Aminophosphonate inhibitors of metallo-β-lactamases NDM-1 and VIM-2.
Palica K, Deufel F, Skagseth S, Di Santo Metzler GP, Thoma J, Andersson Rasmussen A, Valkonen A, Sunnerhagen P, Leiros HS, Andersson H, Erdelyi M. Palica K, et al. Among authors: leiros hs. RSC Med Chem. 2023 Aug 2;14(11):2277-2300. doi: 10.1039/d3md00286a. eCollection 2023 Nov 15. RSC Med Chem. 2023. PMID: 38020072 Free PMC article.
ZN148 Is a Modular Synthetic Metallo-β-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo.
Samuelsen Ø, Åstrand OAH, Fröhlich C, Heikal A, Skagseth S, Carlsen TJO, Leiros HS, Bayer A, Schnaars C, Kildahl-Andersen G, Lauksund S, Finke S, Huber S, Gjøen T, Andresen AMS, Økstad OA, Rongved P. Samuelsen Ø, et al. Among authors: leiros hs. Antimicrob Agents Chemother. 2020 May 21;64(6):e02415-19. doi: 10.1128/AAC.02415-19. Print 2020 May 21. Antimicrob Agents Chemother. 2020. PMID: 32179522 Free PMC article.
Kinetics, Thermodynamics, and Structural Effects of Quinoline-2-Carboxylates, Zinc-Binding Inhibitors of New Delhi Metallo-β-lactamase-1 Re-sensitizing Multidrug-Resistant Bacteria for Carbapenems.
Jia Y, Schroeder B, Pfeifer Y, Fröhlich C, Deng L, Arkona C, Kuropka B, Sticht J, Ataka K, Bergemann S, Wolber G, Nitsche C, Mielke M, Leiros HS, Werner G, Rademann J. Jia Y, et al. Among authors: leiros hs. J Med Chem. 2023 Sep 14;66(17):11761-11791. doi: 10.1021/acs.jmedchem.3c00171. Epub 2023 Aug 16. J Med Chem. 2023. PMID: 37585683
23 results